Protein Alignment sax and acvr1c

DIOPT Version :9

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_002933316.2
• Gene: acvr1c / 100487548
• XenbaseID: XB-GENE-487108
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 220/502 - (43%)
• Similarity: 301/502 - (59%)
• Gaps: 50/502 - (9%)

  Fly    79 CYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPD-QLPMIC-SQNSLKINGP 141
            |..||       ...:|||....||.| .....|:.:..:.|.:.|: :..:.| |.|::
 Frog    74 CLLCE-------NTNYTCQTEGACWTS-VMLTHGKEEVLKSCISLPEFKAQVFCHSSNNI----- 125

  Fly   142 SKRNTGKFVNVVCCAGDYCNEGD--FPELLPFDSN----DVTVITADTSSISKMLVAVLGPFLVI 200
                    ....||..|:||...  .|.:.|..|:    ::|||.  |.||..:.|.::
 Frog   126 --------TRTECCLSDFCNNITLRLPAVTPGVSHMGHVELTVIV--TVSICLLSVVIM------ 174

  Fly   201 ALLGAVTIFFIRRSH-RKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGL 264
                 ||.:..:..: .|..|..:..::|......|      .||.| |::.:....||||||||
 Frog   175 -----VTAYVCQERYCAKNKARRQCVEEPLTECPLD------IAGKS-LKDLIYDMTTSGSGSGL 227

  Fly   265 PLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHEN 329
            |||||||:|:.|.:.|.:|:|::||||||.|.||.:|||||.||||.||.||.|||.|::|||||
 Frog   228 PLLVQRTIARTVVIQELVGKGRFGEVWRGKWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHEN 292

  Fly   330 ILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGK 394
            |||||.:|.....:.|||||::.::..|||||:||.|.::...|:.:.||:.:||.|||.||.|.
 Frog   293 ILGFIAADNKDNGTWTQLWLISEFHEQGSLFDYLNCNTVTIGGMMKLALSVVSGLAHLHMEIVGT 357

  Fly   395 QGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESI 459
            |||||:||||||||||||..|.:|.|||.||||.|..:|..:|:..||:||||||||||:||:||
 Frog   358 QGKPAIAHRDLKSKNILVKKNETCCIADLGLAVKHDSITNTIDIPQNPRVGTKRYMAPELLDDSI 422

  Fly   460 DLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPS 524
            :...|::.:.:|||:.|||.||:.||....|:.:||::|:||:||.|||.||:|||||....|||
 Frog   423 NTYHFDSFKCSDIYSLGLVYWEIARRCSVGGVVDEYQLPYYDMVPSDPSLEDVRKVVCEQKLRPS 487

  Fly   525 IPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADE 571
            |||:|.|...:..|.::|:|||:.|...||.||||||||.:|...::
 Frog   488 IPNQWQSFEALRIMGRIMRECWYANGKARLTALRIKKTISQLCVEED 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	Activin_recp	77..168	CDD:279413	21/92 (23%)
		TM_EGFR-like	182..218	CDD:213052	6/36 (17%)
		TGF_beta_GS	247..274	CDD:285687	16/26 (62%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	166/296 (56%)
		TyrKc	276..553	CDD:197581	153/276 (55%)
acvr1c	XP_002933316.2	Activin_recp	70..139	CDD:366445	20/85 (24%)
		TGF_beta_GS	210..237	CDD:369918	17/27 (63%)
		STKc_TGFbR1_ACVR1b_ACVR1c	243..530	CDD:271045	162/286 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338017at33208
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920