Protein Alignment cn and SQLE

DIOPT Version :9

• Sequence 1: NP_523651.4
• Gene: cn / 35724
• FlyBaseID: FBgn0000337
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_003120.2
• Gene: SQLE / 6713
• HGNCID: 11279
• Length: 574
• Species: Homo sapiens
• Identity: / - (0%)
• Similarity: / - (0%)
• Gaps: / - (0%)

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cn	NP_523651.4	UbiH	31..411	CDD:223727
		NADB_Rossmann	31..353	CDD:304358
SQLE	NP_003120.2	Interaction with MARCHF6. /evidence=ECO:0000269|PubMed:24449766	1..100
		Required for degradation in response to high membrane cholesterol levels. /evidence=ECO:0000269|PubMed:28972164	62..73
		Sufficient for enzyme activity. /evidence=ECO:0000269|PubMed:10666321, ECO:0000269|PubMed:30626872	118..574
		FAD_binding_3	122..>427	CDD:332373
		NADB_Rossmann	277..548	CDD:328723
		Hydrophobic, mediates interaction with membranes. /evidence=ECO:0000269|PubMed:30626872	516..574

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910