DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cn and Kmo

DIOPT Version :9

Sequence 1:	NP_523651.4	Gene:	cn / 35724	FlyBaseID:	FBgn0000337	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_006250387.1	Gene:	Kmo / 59113	RGDID:	620610	Length:	503	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	197/415 - (47%)
Similarity:	271/415 - (65%)	Gaps:	5/415 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RRVAVIGAGLVGSLAALNFARMGNHVDLYEYREDIRQALVVQGRSINLALSQRGRKALAAVGLEQ 93
            :||.|||.||||:|.|...|:....||:||.|||||.|..::|||||||||.|||:||.|||||.
  Rat     9 KRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRGRSINLALSYRGRQALKAVGLED 73

  Fly    94 EVLATAIPMRGRMLHDVRGNSSVVLYDPINNQCLYSVGRRQLNEVLLNACDKLPNIRCHFEHKLT 158
            ::::..:||:.||:|.:.|..|.:.|.. .:|.:.|:.|.:||:.||.|.:..||.:.||.|||:
  Rat    74 QIVSKGVPMKARMIHSLSGKKSAIPYGN-KSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLS 137

  Fly   159 SANLREGSMEFRNPAKEAVAAHADLIVGCDGAFSSVRQNNVRLPGFNYSQEYIETGYLELCIPSK 223
            .....||.:....|.|.......|||||||||:|:||.:.::.|.|:|||:||..||:||.||.|
  Rat   138 KCCPEEGILTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPPK 202

  Fly   224 SGDFQMPANYLHIWPRNTFMMIALPNQDKSFTVTLSMPFEIFAGIQNQNDLLEFFKLNFRDALPL 288
            :|::.|..|.|||||||.||||||||.|||||.||.|.||.|..:...:|:|:||:.||.||:||
  Rat   203 NGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTHSDVLDFFQKNFPDAIPL 267

  Fly   289 IGEQQLIKDFFKTRPQFLVSIKCRPYHYADKALILGDAAHAMVPYYGQGMNAGMEDVTLLTDILA 353
            :|||.|::|||....|.::|:||.|:|...:.:::||||||:||::|||||||.||..:..:::.
  Rat   268 MGEQALMRDFFLLPAQPMISVKCSPFHLKSRCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMD 332

  Fly   354 K-QLPLDETLALFTESRWQDAFAICDLAMYNYVEMR-DLTKRWTFRLRKWLDTLLFRLFPG-WIP 415
            | ...|...|..|:..|..|..||.||:||||:||| .:..|| |..::.||..|..|.|. :||
  Rat   333 KFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRW-FLFQRLLDKFLHALMPSTFIP 396

  Fly   416 LYNSVSFSSMPYRQCIANRKWQDQL 440
            ||..|:|:.:.|.:.:....||.::
  Rat   397 LYTMVAFTRIRYHEAVLRWHWQKKI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cn	NP_523651.4	UbiH	31..411	CDD:223727	186/381 (49%)
cn	NP_523651.4	NADB_Rossmann	31..353	CDD:304358	162/321 (50%)
Kmo	XP_006250387.1	UbiH	24..396	CDD:223727	178/373 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	327	1.000	Domainoid score	I1143
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2729
Inparanoid	1	1.050	384	1.000	Inparanoid score	I1968
OMA	1	1.010	-	-		QHG55558
OrthoDB	1	1.010	-	-		D268134at33208
OrthoFinder	1	1.000	-	-		FOG0003209
OrthoInspector	1	1.000	-	-		oto97440
orthoMCL	1	0.900	-	-		OOG6_103174
Panther	1	1.100	-	-	LDO	PTHR46028
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4199
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980