DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1946 and Awat2

DIOPT Version :9

Sequence 1:	NP_610319.2	Gene:	CG1946 / 35720	FlyBaseID:	FBgn0033216	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001178653.1	Gene:	Awat2 / 302425	RGDID:	1565111	Length:	333	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	107/338 - (31%)
Similarity:	176/338 - (52%)	Gaps:	30/338 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PLERRLQTLVTSFFTYTFFTLPISSCLAVAILLYYGEMF-----VRSLLLIYFVKIYLDYK---- 66
            |.::.|:|.:..|..:.:....:...:.|.::..|..:|     |..|:|::   :..|:|
  Rat     4 PTKKDLKTAMEVFALFQWALSALVIVITVIMVNLYLVVFTSFWPVTVLMLLW---LAFDWKTPER 65

  Fly    67 --RNYGIMEGNGWLFYRSNWRYRNYFPVELVKTAELPPNRNYIVASFPHGILGTGTCINMSLDID 129
              |.:..:  ..|..::   .|.||||:::|||.::|.|.|||:|..|||:|......:.|.|..
  Rat    66 GGRRFNCV--RRWCLWK---HYSNYFPLKIVKTKDIPTNHNYILACHPHGLLSHSWFGHFSTDTT 125

  Fly   130 NWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDNRDGFTSNA 194
            .:..::|.:.|.:.||...|..||||:.:...|..|||:.|:.:||::..           |.|.
  Rat   126 GFSKIFPGITPYMLTLGAFFWVPFLREYIMSTGACSVSQSSIDFLLTQKG-----------TGNM 179

  Fly   195 VAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTGSSIVPSLSFGEVDIFDQVANPPDSSLRR 259
            :.|:|||..|...|.||...|.||.|:|||:.|:|.|.|::|:.:|||.|::||....|.|.:..
  Rat   180 LVVVVGGLAECKYSMPGSTTLFLKKRQGFVRTALRYGVSLIPAYAFGEADLYDQHIFTPGSFISH 244

  Fly   260 FQNVVKKFTGISPLLPKGRGIFNYNYGILPHRRRIVQVVGSPIDVERCETPDPEYVDKIHGQVID 324
            ||...:|...:.|....|||....::|:||:.:.:..:||.|:.:.:.|.|..|.|.|.|...||
  Rat   245 FQKWFQKMVHVYPCAFYGRGFTKNSWGLLPYSQPVTTIVGEPLPLPKIENPSQEIVAKYHTLYID 309

  Fly   325 ALARMFDEYKEKY 337
            ||.::||::|.|:
  Rat   310 ALRKLFDQHKTKF 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1946	NP_610319.2	LPLAT	80..349	CDD:302626	93/258 (36%)
Awat2	NP_001178653.1	LPLAT	38..332	CDD:418432	102/304 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340458
Domainoid	1	1.000	212	1.000	Domainoid score	I2683
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3307
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm9114
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.870