Protein Alignment CG1946 and AWAT2

DIOPT Version :10

• Sequence 1: NP_610319.2
• Gene: CG1946 / 35720
• FlyBaseID: FBgn0033216
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_001002254.1
• Gene: AWAT2 / 158835
• HGNCID: 23251
• Length: 333
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 112/346 - (32%)
• Similarity: 180/346 - (52%)
• Gaps: 44/346 - (12%)

  Fly    10 VPLERRLQTLVTSF--FTYTFFTLPISSCLAVAILLY------YGEMFVRSLLLIYFVKIYLDYK 66
            :|.::.|:|.:..|  |.::|..|.|::.: :|:.||      |..:.|..|..:.|     |:|
Human     3 LPSKKDLKTALDVFAVFQWSFSALLITTTV-IAVNLYLVVFTPYWPVTVLILTWLAF-----DWK 61

  Fly    67 ------RNYGIMEGNGWLFYRSNWR----YRNYFPVELVKTAELPPNRNYIVASFPHGILGTGTC 121
                  |.:..:.         :||    |.:|||::|:||.::.|:||||:...|||:...|..
Human    62 TPQRGGRRFTCVR---------HWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWF 117

  Fly   122 INMSLDIDNWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDN 186
            .:.:.:...:..::|.:.|.|.||...|..||||:.:...|..|||:.|:.:||:      ||.
Human   118 GHFATEASGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLT------HKG- 175

  Fly   187 RDGFTSNAVAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTGSSIVPSLSFGEVDIFDQVAN 251
                |.|.|.|::||..|...|.||...|.||:|.|||:||::.|..::|:.:|||.|::||...
Human   176 ----TGNMVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIF 236

  Fly   252 PPDSSLRRFQNVVKKFTGISPLLPKGRGIFNYNYGILPHRRRIVQVVGSPIDVERCETPDPEYVD 316
            .|...:.|||...:....|.|....|||....::|:||:.|.:..:||.|:.:.:.|.|..|.|.
Human   237 TPGGFVNRFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVA 301

  Fly   317 KIHGQVIDALARMFDEYKEKY 337
            |.|...||||.::||::|.|:
Human   302 KYHTLYIDALRKLFDQHKTKF 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1946	NP_610319.2	LPLAT	80..349	CDD:473073	94/262 (36%)
AWAT2	NP_001002254.1	LPLAT	38..332	CDD:473073	102/310 (33%)