Protein Alignment Dgat2 and MOGAT2

DIOPT Version :9

• Sequence 1: NP_610318.1
• Gene: Dgat2 / 35719
• FlyBaseID: FBgn0033215
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_011543569.1
• Gene: MOGAT2 / 80168
• HGNCID: 23248
• Length: 336
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 120/303 - (39%)
• Similarity: 171/303 - (56%)
• Gaps: 26/303 - (8%)

  Fly     3 IEWAPLRVPLERRLQIL-VTAFFTSMLLI--LLSVSFLLVAGSLIYGGLLVR--SLMVTYLAYVF 62
            :|:|||.:|.|||||.| |..|..|.|.:  :.:|.|:.:        |..|  .|.|.|.|:.:
Human     2 VEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIAL--------LFTRFWLLTVLYAAWWY 58

  Fly    63 VHHKKTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINM 127
            :...|.:.  .|......|...:.::.:||||:.|||||||..::|||....|||:|..|...|:
Human    59 LDRDKPRQ--GGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANL 121

  Fly   128 GLEISKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDG 192
            ..|.:.:..:||.:||.|..|...|..||.|:.:...|||:..||:...:|          ||.|
Human   122 CTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHIL----------NRKG 176

  Fly   193 FTSNAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPN 257
             ..|.:.|:|||||||:|:.||.:.|.|:|||||||:|:..|:.:||.|||||.|:|||:.|...
Human   177 -GGNLLGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG 240

  Fly   258 SLLRRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQV 300
            |.||..|:.::|:.|:|..:..|||.|.|:||.:|:||.|..|
Human   241 SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTV 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	96/227 (42%)
MOGAT2	XP_011543569.1	LPLAT	41..297	CDD:302626	103/264 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146800
Domainoid	1	1.000	214	1.000	Domainoid score	I2726
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57020
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3400
Isobase	1	0.950	-	0	Normalized mean entropy	S1346
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8637
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R305
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750