DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dgat2 and Mogat2

DIOPT Version :9

Sequence 1:	NP_610318.1	Gene:	Dgat2 / 35719	FlyBaseID:	FBgn0033215	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001102906.2	Gene:	Mogat2 / 681211	RGDID:	1598060	Length:	334	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	136/355 - (38%)
Similarity:	199/355 - (56%)	Gaps:	39/355 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEWAPLRVPLERRLQ---ILVTAFFTSMLLILLSVSFLLVAGSLIY---GGLLVRSLM--VTYLA 59
            :|:|||.||.|||||   :|...|           |||.:|...|:   |.|..|..:  |.|..
  Rat     2 VEFAPLLVPWERRLQTFAVLQWVF-----------SFLALAQLCIFIFIGLLFTRFWLFSVLYAT 55

  Fly    60 YVFVHHKKTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIG 124
            :.::...:.:.  .|......|...:.::.:|:|||.|||||||..::|||....|||:|..|..
  Rat    56 WWYLDWDRPRQ--GGRPIQFFRRMAIWKYMKDFFPVSLVKTAELDPSRNYIAGFHPHGVLAAGAF 118

  Fly   125 INMGLEISKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDN 189
            :|:..|.:.:..|||.:|..|..|...|..|..|:.:...||||..|.:...:||:...
  Rat   119 LNLCTESTGFTSLFPGIRSYLMMLTVWFRAPIFRDYIMSGGLVSSEKVSADHILSRKGG------ 177

  Fly   190 RDGFTSNAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVAN 254
                 .|.:||:|||||||:|:.||.|.|.|||||||:|:|:..|:::||.|||||.::|:||.|
  Rat   178 -----GNLLAIIVGGAQEALDARPGAYRLLLKNRKGFIRLALTHGAALVPIFSFGENNLFNQVEN 237

  Fly   255 PPNSLLRRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVD 319
            .|.:.||..|::::|:.|:|..:..|||.|.|:||.:|||:.|..|||.||:|....||..|.|:
  Rat   238 TPGTWLRWIQNWLQKIMGISLPLFHGRGVFQYSFGLVPFRQPITTVVGKPIEVQMIPHPSEEEVN 302

  Fly   320 KVHGQVIESLEKLFDQYK-------DKYLE 342
            ::|...|:.|.|||:::|       |::||
  Rat   303 RLHQLYIKELCKLFEEHKLKFNVPEDQHLE 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	111/272 (41%)
Mogat2	NP_001102906.2	LPLAT	41..333	CDD:418432	117/305 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340456
Domainoid	1	1.000	212	1.000	Domainoid score	I2683
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57020
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3307
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm9114
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770