DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dgat2 and Awat1

DIOPT Version :9

Sequence 1:	NP_610318.1	Gene:	Dgat2 / 35719	FlyBaseID:	FBgn0033215	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001102841.1	Gene:	Awat1 / 679520	RGDID:	1587163	Length:	328	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	114/334 - (34%)
Similarity:	176/334 - (52%)	Gaps:	41/334 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 FFTSMLLILLSVSFLLVAG-------SLIYGGL-LVRSLMVTYLAYVFVHHKKTQS--------V 71
            :..|:.|:...:|:|.:..       ||.:..| |:.||.|.:    |:...||.:        |
  Rat     9 YLQSLSLLQWPLSYLAIFWIVQPLFFSLFFTPLWLLPSLYVVW----FILDWKTPNQGGRRSAWV 69

  Fly    72 VDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLEISKWLE 136
            .:.|.|         .|.|||||:.::||.:|..::|||:...|||:|..|...|...|.:.:.:
  Rat    70 RNWNIW---------THIRDYFPITILKTKDLSPSQNYIMGVHPHGLLTFGAFCNFCTEATGFSK 125

  Fly   137 LFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTSNAVAIL 201
            .||.:.|.|.||...|.:|.:|:.:...|:.|||:.::..:||..            |.|.|.|:
  Rat   126 TFPGITPHLATLSWFFKIPLIRDYIMAKGVCSVSQASIDYLLSHG------------TGNLVGIV 178

  Fly   202 VGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLLRRFQDF 266
            |||..||:.|.|....|.||.||||||.|:|.|:.:||:|:|||.:::|||.....|.:.:||.|
  Rat   179 VGGVGEALQSVPNTTTLILKKRKGFVRTALRHGAHLVPTFTFGETEVYDQVVFHEESRMFKFQSF 243

  Fly   267 VKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVDKVHGQVIESLEK 331
            .:::.|....:..|:||.....|.||:.|.||.|||.|:.:.:.::|..|.|||.|...:::|.|
  Rat   244 FRRIFGFYFCVFYGQGFHQECKGLLPYHRPIVTVVGEPLPLPQVKNPSPEIVDKYHALYMDALYK 308

  Fly   332 LFDQYKDKY 340
            ||:|:|.:|
  Rat   309 LFEQHKVQY 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	98/265 (37%)
Awat1	NP_001102841.1	LPLAT	34..327	CDD:302626	110/309 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340453
Domainoid	1	1.000	212	1.000	Domainoid score	I2683
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3307
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm9114
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.870