DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dgat2 and CG1946

DIOPT Version :9

Sequence 1:	NP_610318.1	Gene:	Dgat2 / 35719	FlyBaseID:	FBgn0033215	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_610319.2	Gene:	CG1946 / 35720	FlyBaseID:	FBgn0033216	Length:	349	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	236/351 - (67%)
Similarity:	283/351 - (80%)	Gaps:	3/351 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKIEWAPLRVPLERRLQILVTAFFTSMLLILLSVSFLLVAGSLIYGGLLVRSLMVTYLAYVFVHH 65
            |.|||||||||||||||.|||:|||.....|...|.|.||..|.||.:.||||::.|...:::.:
  Fly     1 MTIEWAPLRVPLERRLQTLVTSFFTYTFFTLPISSCLAVAILLYYGEMFVRSLLLIYFVKIYLDY 65

  Fly    66 KKTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLE 130
            |:...:::||||:..|:|.   .||:|||||||||||||..:|||:|||||||||||..|||.|:
  Fly    66 KRNYGIMEGNGWLFYRSNW---RYRNYFPVELVKTAELPPNRNYIVASFPHGILGTGTCINMSLD 127

  Fly   131 ISKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTS 195
            |..||.|:|.||||:.|||.||..||:|::||.||:||||||:|..:|||||||.||||||||||
  Fly   128 IDNWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDNRDGFTS 192

  Fly   196 NAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLL 260
            ||||:|||||:|||||||||||||||:|||||:||:|||||||||.|||||||||||||||:|.|
  Fly   193 NAVAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTGSSIVPSLSFGEVDIFDQVANPPDSSL 257

  Fly   261 RRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVDKVHGQV 325
            ||||:.|||.||:|||:|.|||.|||.:|.||.|||||||||:||||.:.|.||.|||||:||||
  Fly   258 RRFQNVVKKFTGISPLLPKGRGIFNYNYGILPHRRRIVQVVGSPIDVERCETPDPEYVDKIHGQV 322

  Fly   326 IESLEKLFDQYKDKYLENSKSATLVV 351
            |::|.::||:||:||..|||...|::
  Fly   323 IDALARMFDEYKEKYTPNSKHIKLII 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	194/265 (73%)
CG1946	NP_610319.2	LPLAT	80..349	CDD:302626	196/272 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448347
Domainoid	1	1.000	93	1.000	Domainoid score	I2557
eggNOG	1	0.900	-	-		E1_KOG0831
Homologene	1	1.000	-	-		H57020
Inparanoid	1	1.050	93	1.000	Inparanoid score	I2247
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm6422
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	P	PTHR12317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R305
SonicParanoid	1	1.000	-	-		X186
	14	13.840