DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dgat2 and CG1941

DIOPT Version :9

Sequence 1:	NP_610318.1	Gene:	Dgat2 / 35719	FlyBaseID:	FBgn0033215	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	257/352 - (73%)
Similarity:	298/352 - (84%)	Gaps:	0/352 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKIEWAPLRVPLERRLQILVTAFFTSMLLILLSVSFLLVAGSLIYGGLLVRSLMVTYLAYVFVHH 65
            |||||||..||:|||.|....||.....:||...|:..||..|.||.||.|::||.||.||:.:|
  Fly     1 MKIEWAPKGVPMERRRQTFAMAFLILSFMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYVYANH 65

  Fly    66 KKTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLE 130
            |:|.|::|||||.|.|.|.|.|||||||||:||||||||..|||||||||||||||||.|||||:
  Fly    66 KRTHSIMDGNGWKINRNNWLFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGLD 130

  Fly   131 ISKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTS 195
            |||||:||||||||:.||||:|..|.:|.:||.|||||||||||:.:|:||||||||||||||||
  Fly   131 ISKWLQLFPQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFTS 195

  Fly   196 NAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLL 260
            |||||||||||||:|||||:||||||||||||:|||||||||||:||||||||.|||||||||.:
  Fly   196 NAVAILVGGAQEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSRV 260

  Fly   261 RRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVDKVHGQV 325
            ||||||||::||:|||||||||.|||:|||||.|||||||||||||||:::.||:.||||:|.||
  Fly   261 RRFQDFVKRITGISPLIPVGRGIFNYSFGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDKIHKQV 325

  Fly   326 IESLEKLFDQYKDKYLENSKSATLVVH 352
            |:.|||:|.:|||:|:.|||...|::|
  Fly   326 IDDLEKMFAKYKDQYIPNSKQDKLIIH 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	214/265 (81%)
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	226/289 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448346
Domainoid	1	1.000	93	1.000	Domainoid score	I2557
eggNOG	1	0.900	-	-		E1_KOG0831
Homologene	1	1.000	-	-		H57020
Inparanoid	1	1.050	93	1.000	Inparanoid score	I2247
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm6422
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	P	PTHR12317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R305
SonicParanoid	1	1.000	-	-		X186
	14	13.840