DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dgat2 and Awat1

DIOPT Version :9

Sequence 1:	NP_610318.1	Gene:	Dgat2 / 35719	FlyBaseID:	FBgn0033215	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001074605.1	Gene:	Awat1 / 245533	MGIID:	3588200	Length:	328	Species:	Mus musculus

Alignment Length:	277	Identity:	100/277 - (36%)
Similarity:	153/277 - (55%)	Gaps:	25/277 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KKTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLE 130
            :::..|.:.|.|         .|.|||||:.::||.:|..::|||:...|||:|..|...|...|
Mouse    64 RRSDWVRNWNVW---------NHIRDYFPITILKTKDLSPSENYIMGVHPHGLLTFGAFCNFCTE 119

  Fly   131 ISKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTS 195
            .:.:.:.||.:.|.|.||...|.:|.:|:.:...||.|||:.::..:||..            |.
Mouse   120 ATGFSKTFPGITPHLATLSWFFKIPIIRDYIMAKGLCSVSQASIDYLLSHG------------TG 172

  Fly   196 NAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLL 260
            |.|.|:|||..||:.|.|....|.||.||||||.|::.|:.:||:|:|||.:::|||....:|.:
Mouse   173 NLVGIVVGGVGEALQSVPNTTTLLLKKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHEDSRM 237

  Fly   261 RRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVG--APIDVVKNEHPDSEYVDKVHG 323
            .:||...:::.|....:..|:||.....|.||:.:.|:.|||  .|:..|||  |..|.|||.|.
Mouse   238 FKFQSLFRRIFGFYCCVFYGQGFHQDCKGLLPYHKPIITVVGEALPLPQVKN--PSPEIVDKYHA 300

  Fly   324 QVIESLEKLFDQYKDKY 340
            ..:::|.|||:|:|.:|
Mouse   301 LYMDALYKLFEQHKVQY 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	98/267 (37%)
Awat1	NP_001074605.1	LPLAT	36..327	CDD:302626	100/277 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836755
Domainoid	1	1.000	217	1.000	Domainoid score	I2664
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3298
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8869
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.870