Protein Alignment Dgat2 and AWAT2

DIOPT Version :9

• Sequence 1: NP_610318.1
• Gene: Dgat2 / 35719
• FlyBaseID: FBgn0033215
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001002254.1
• Gene: AWAT2 / 158835
• HGNCID: 23251
• Length: 333
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 114/339 - (33%)
• Similarity: 187/339 - (55%)
• Gaps: 27/339 - (7%)

  Fly    10 VPLERRLQILVTAF------FTSMLL--ILLSVSFLLVAGSLIYGGLLVRSLMVTYLAYVFVHHK 66
            :|.::.|:..:..|      |:::|:  .:::|:..||..:..:.   |..|::|:||:.:   |
Human     3 LPSKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWP---VTVLILTWLAFDW---K 61

  Fly    67 KTQSVVDGNGWMITRTNLLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLEI 131
            ..|.  .|..:...|...|.:||.||||::|:||.::..::||||...|||:...|...:...|.
Human    62 TPQR--GGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHFATEA 124

  Fly   132 SKWLELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTSN 196
            |.:.::||.:.|.:.||...|.:||:||.:...|..|||:.::..:|:      ||.     |.|
Human   125 SGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLT------HKG-----TGN 178

  Fly   197 AVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLLR 261
            .|.:::||..|...|.||...|.||||.||||||::.|..::|:::|||.|::||....|...:.
Human   179 MVIVVIGGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGGFVN 243

  Fly   262 RFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDVVKNEHPDSEYVDKVHGQVI 326
            |||.:.:.:..:.|....||||...::|.||:.|.:..:||.|:.:.|.|:|..|.|.|.|...|
Human   244 RFQKWFQSMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYI 308

  Fly   327 ESLEKLFDQYKDKY 340
            ::|.|||||:|.|:
Human   309 DALRKLFDQHKTKF 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	98/265 (37%)
AWAT2	NP_001002254.1	LPLAT	38..332	CDD:388412	108/304 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146794
Domainoid	1	1.000	214	1.000	Domainoid score	I2726
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3400
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8637
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.870