Protein Alignment Dgat2 and AWAT1

DIOPT Version :9

• Sequence 1: NP_610318.1
• Gene: Dgat2 / 35719
• FlyBaseID: FBgn0033215
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_016884784.1
• Gene: AWAT1 / 158833
• HGNCID: 23252
• Length: 395
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 115/389 - (29%)
• Similarity: 176/389 - (45%)
• Gaps: 86/389 - (22%)

  Fly    24 FTSMLLILLSVSFLLVAGSL--IYGGLLVRSLM---VTYLAYVFVHHKKTQSVVDGNGWMITRTN 83
            |.|::|:...:|:|.:...|  ::..||..||.   |.|.|::|:..|..:.....:.|:  |..
Human    10 FQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWV--RNW 72

  Fly    84 LLHRHYRDYFPVELVKTAELPATKNYILASFPHGILGTGIGINMGLEISKWLELFPQVRPKLGTL 148
            .:..|.|||||:.::||.:|....||::...|||:|..|...|...|.:.:.:.||.:.|.|.||
Human    73 CVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATL 137

  Fly   149 DQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFTSNAVAILVGGAQEAMDSHP 213
            ...|.:||:||.|...|:.|||:.|:..:||..            |.|.|.|:|||..||:.|.|
Human   138 SWFFKIPFVREYLMAKGVCSVSQPAINYLLSHG------------TGNLVGIVVGGVGEALQSVP 190

  Fly   214 GQYILTLKNRKGFVRMAIRTGSSIVPSFSFGEVDIFDQVANPPNSLLRRFQDFVKKLTGVSPLIP 278
            ....|.|:.||||||.|::.|:.:||:|:|||.:::|||....:|.:.:||...:::.|....:.
Human   191 NTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVF 255

  Fly   279 VGRGFFNYTFGFLPFRRRIVQV------------------------------------------- 300
            .|:.|...:.|.||:.|.||.|
Human   256 YGQSFCQGSTGLLPYSRPIVTVGECHSQPQCHLRFLNLNLSLAPPKKRAAEGKVGADLGCESQAQ 320

  Fly   301 ------------------------VGAPIDVVKNEHPDSEYVDKVHGQVIESLEKLFDQYKDKY 340
                                    ||.|:.:.:.|.|..|.|||.|...:::|.|||||:|..|
Human   321 GRRGRLKEEEVLTLSSSLFRSLLAVGEPLPLPQIEKPSQEMVDKYHALYMDALHKLFDQHKTHY 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgat2	NP_610318.1	LPLAT	74..340	CDD:302626	99/332 (30%)
AWAT1	XP_016884784.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146803
Domainoid	1	1.000	214	1.000	Domainoid score	I2726
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3400
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8637
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.870