DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1941 and Dgat2l6

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001107556.1	Gene:	Dgat2l6 / 668257	MGIID:	3045268	Length:	337	Species:	Mus musculus

Alignment Length:	345	Identity:	125/345 - (36%)
Similarity:	189/345 - (54%)	Gaps:	44/345 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEWAPKGVPMERRRQTFAMAFLILSFMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYVYANHKR 67
            ::|.|              .:::|..:.:....|.    :||  :.|| .:.|::||:: |....
Mouse    19 LQWIP--------------VYVLLGTLSILGMPYL----LLF--TTLW-PLSVLFLVWI-AYDWN 61

  Fly    68 THSIMDG--NGWKINRNNW-LFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGL 129
            || |.||  :.|.   .|| |:::::.||||:||||.:|.|..|||:.|.|||||..|..||...
Mouse    62 TH-IQDGRRSAWV---RNWTLWKYFQSYFPVKLVKTHDLSPKHNYIILSHPHGILSYGAFINFAT 122

  Fly   130 DISKWLQLFPQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFT 194
            :.:.:.::||.:.|.:|||:..|..|.||..|.|.|:..|||.:|.:.||:      ||     :
Mouse   123 ESTGFSRVFPSITPFLATLEGIFWIPFVRDYLMSLGICPVSKLSLTHKLTQ------KD-----S 176

  Fly   195 SNAVAILVGGAQEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSR 259
            .|||.|:.|||.|:|.|.||..::.||.|:||||:|::||:.:||::||||.:..:|......:.
Mouse   177 GNAVIIVPGGASESLLSRPGVSMIYLKKRQGFVKLALKTGAYLVPSYSFGENETYNQETFAEGTW 241

  Fly   260 VRRFQDFV----KRITGISPLIPVGRGIFNYSFGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDK 320
            :|.||..:    |||.||:.....|||:...|:||||....|..|||.|:.|.:...||...|:|
Mouse   242 LRFFQKNIQKIGKRILGINLCTIHGRGLTRGSWGFLPFNHPITTVVGEPLPVPKIPDPDKETVEK 306

  Fly   321 IHKQVIDDLEKMFAKYKDQY 340
            ..:..|..|.|:|.::|.:|
Mouse   307 YLELYISALRKLFDQHKAEY 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	117/296 (40%)
Dgat2l6	NP_001107556.1	LPLAT	38..336	CDD:302626	122/312 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836759
Domainoid	1	1.000	217	1.000	Domainoid score	I2664
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3298
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8869
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.770