DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1941 and dgat2

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001025367.1	Gene:	dgat2 / 565316	ZFINID:	ZDB-GENE-050913-15	Length:	361	Species:	Danio rerio

Alignment Length:	345	Identity:	115/345 - (33%)
Similarity:	184/345 - (53%)	Gaps:	43/345 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FAMAFLILS-----FMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYVYANHKRTHSIMDGNGWK 78
            |.|.||.:.     .::..|.:.|:|.:||:          |.:|:|.:..        .|.|.:
Zfish    49 FIMTFLTMGIACSLLLMYMFCTDFWVISVLY----------VAWLIYDWNT--------PGQGGR 95

  Fly    79 INRNNW-----LFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGLDISKWLQLF 138
              |:.|     ::::.|||||::|:||..|.|::|||....|||||..|...|.|.:.:.:.::|
Zfish    96 --RSTWVRDWTVWKYMRDYFPIRLIKTHNLLPSRNYIFGYHPHGILCFGAFCNFGTEATGFTKVF 158

  Fly   139 PQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFTSNAVAILVG 203
            |.::|.:|||..||..|:.|..|...|:..|::.::.|||:.:.           |.|||.|::|
Zfish   159 PGIKPSLATLAGNFRLPMFREYLMCGGICPVNRNSIDYLLSSNG-----------TGNAVVIVIG 212

  Fly   204 GAQEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSRVRRFQDFVK 268
            ||.|:||..||:..:.||.||||||:|::.|:.:||.:||||.::..|:.....|..|..|..::
Zfish   213 GAAESLDCAPGRNSVMLKKRKGFVKLALKQGADLVPVYSFGENEVYKQLIFEEGSWWRTIQRKLQ 277

  Fly   269 RITGISPLIPVGRGI-FNYSFGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDKIHKQVIDDLEKM 332
            :..|.:|.:..|.|: |..|:|.:|..:.|..|||.||.|.:.::|....:|..|...|..|:.:
Zfish   278 KFLGFAPCLFHGCGLFFPESWGLVPYCKPITTVVGEPITVPKIEEPTQDVIDMYHAMYIRSLKSL 342

  Fly   333 FAKYKDQYIPNSKQDKLIIH 352
            |..||.::..| :.|.||||
Zfish   343 FDNYKTRFGLN-ESDTLIIH 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	100/295 (34%)
dgat2	NP_001025367.1	DAGAT	65..360	CDD:112781	108/326 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580241
Domainoid	1	1.000	205	1.000	Domainoid score	I2878
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3466
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm6422
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R305
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.940