DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1941 and Awat2

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001178653.1	Gene:	Awat2 / 302425	RGDID:	1565111	Length:	333	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	103/335 - (30%)
Similarity:	176/335 - (52%)	Gaps:	24/335 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FAMAFLILSFMILSFGSYFFVAAVLFYGSLLW--RTIMVIYLVYVYANHKRTHSIMDGNGWKINR 81
            :|::.|::...::....|.    |:|  :..|  ..:|:::|.:.:...:|     .|..:...|
  Rat    21 WALSALVIVITVIMVNLYL----VVF--TSFWPVTVLMLLWLAFDWKTPER-----GGRRFNCVR 74

  Fly    82 NNWLFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGLDISKWLQLFPQVRPKVA 146
            ...|::||.:|||:::|||.::|.|.|||||..|||:|......:...|.:.:.::||.:.|.:.
  Rat    75 RWCLWKHYSNYFPLKIVKTKDIPTNHNYILACHPHGLLSHSWFGHFSTDTTGFSKIFPGITPYML 139

  Fly   147 TLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFTSNAVAILVGGAQEALDS 211
            ||...|..|.:|..:.|.|..|||:.::.:|||:..           |.|.:.::|||..|...|
  Rat   140 TLGAFFWVPFLREYIMSTGACSVSQSSIDFLLTQKG-----------TGNMLVVVVGGLAECKYS 193

  Fly   212 HPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSRVRRFQDFVKRITGISPL 276
            .||...|.||.|:|||:.|:|.|.|::|.::|||.|:.||....|.|.:..||.:.:::..:.|.
  Rat   194 MPGSTTLFLKKRQGFVRTALRYGVSLIPAYAFGEADLYDQHIFTPGSFISHFQKWFQKMVHVYPC 258

  Fly   277 IPVGRGIFNYSFGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDKIHKQVIDDLEKMFAKYKDQYI 341
            ...|||....|:|.||..:.:..:||.|:.:.:.:.|....|.|.|...||.|.|:|.::|.::.
  Rat   259 AFYGRGFTKNSWGLLPYSQPVTTIVGEPLPLPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFG 323

  Fly   342 PNSKQDKLII 351
            .:..|:.:||
  Rat   324 ISETQELVII 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	95/291 (33%)
Awat2	NP_001178653.1	LPLAT	38..332	CDD:418432	99/315 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340460
Domainoid	1	1.000	212	1.000	Domainoid score	I2683
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3307
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm9114
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.870