DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1941 and Awat1

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001074605.1	Gene:	Awat1 / 245533	MGIID:	3588200	Length:	328	Species:	Mus musculus

Alignment Length:	323	Identity:	116/323 - (35%)
Similarity:	172/323 - (53%)	Gaps:	19/323 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LSFGSYFFVAAVLFYGSL---LWRTIMVIYLVYVYANHKRTHSIMDGNGWKINRNNWLFRHYRDY 92
            ||:.:.|::...|....|   || .:..:|.|::..:.|........:.|..|.|.|  .|.|||
Mouse    20 LSYVAMFWIVQPLLICLLFTPLW-PLPTVYFVWLLLDWKTPDKGGRRSDWVRNWNVW--NHIRDY 81

  Fly    93 FPVQLVKTAELPPNKNYILASFPHGILGTGISINMGLDISKWLQLFPQVRPKVATLDQNFLTPIV 157
            ||:.::||.:|.|::|||:...|||:|..|...|...:.:.:.:.||.:.|.:|||...|..||:
Mouse    82 FPITILKTKDLSPSENYIMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPII 146

  Fly   158 RGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFTSNAVAILVGGAQEALDSHPGKYILTLKN 222
            |..:.:.||.|||:.::.|||:..            |.|.|.|:|||..|||.|.|....|.||.
Mouse   147 RDYIMAKGLCSVSQASIDYLLSHG------------TGNLVGIVVGGVGEALQSVPNTTTLLLKK 199

  Fly   223 RKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSRVRRFQDFVKRITGISPLIPVGRGIFNYS 287
            |||||:.|::.|:.:||||:|||.::.|||....:||:.:||...:||.|....:..|:|.....
Mouse   200 RKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHEDSRMFKFQSLFRRIFGFYCCVFYGQGFHQDC 264

  Fly   288 FGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDKIHKQVIDDLEKMFAKYKDQYIPNSKQDKLI 350
            .|.||..:.|:.|||..:.:.|...|....|||.|...:|.|.|:|.::|.||..::.| |||
Mouse   265 KGLLPYHKPIITVVGEALPLPQVKNPSPEIVDKYHALYMDALYKLFEQHKVQYGCSNTQ-KLI 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	104/289 (36%)
Awat1	NP_001074605.1	LPLAT	36..327	CDD:302626	112/307 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836756
Domainoid	1	1.000	217	1.000	Domainoid score	I2664
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3298
Isobase	1	0.950	-	0	Normalized mean entropy	S1864
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8869
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.820