DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1941 and TMEM68

DIOPT Version :9

Sequence 1:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001273586.1	Gene:	TMEM68 / 137695	HGNCID:	26510	Length:	324	Species:	Homo sapiens

Alignment Length:	232	Identity:	55/232 - (23%)
Similarity:	91/232 - (39%)	Gaps:	53/232 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LSFGSYF---FVAAVLFYGSLLWRTIMVIYLVYVYAN-HKR--------THSIMDG------NGW 77
            |:|.:|.   |...:|..  |.:.||.::||..::.: :||        :|::.||      ..|
Human    38 LNFANYLLWVFTPLILLI--LPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLW 100

  Fly    78 KINRNNWLFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGLDISKWLQLFPQVR 142
            ..:...|   |..:      |...|..|.....|..|.||    .|.|:....::|   :|....
Human   101 DGHAAVW---HGYE------VHGMEKIPEDGPALIIFYHG----AIPIDFYYFMAK---IFIHKG 149

  Fly   143 PKVATLDQNFL--TPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFTSNAVAILVGGA 205
            .....:..:|:  .|....||..:..:...:|..|.:|           |.|   :.:||..||.
Human   150 RTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEIL-----------RSG---HLLAISPGGV 200

  Fly   206 QEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFS 242
            :|||.|.. .|.:...:|:||.::||.....|:|.|:
Human   201 REALISDE-TYNIVWGHRRGFAQVAIDAKVPIIPMFT 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	49/210 (23%)
TMEM68	NP_001273586.1	LPLAT_MGAT-like	103..310	CDD:153249	39/165 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910