Protein Alignment tor and Lyn

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_110484.1
• Gene: Lyn / 81515
• RGDID: 621017
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 681
• Identity: 155/681 - (22%)
• Similarity: 234/681 - (34%)
• Gaps: 254/681 - (37%)

  Fly   250 DKQYHVGVRTVNIMNRLESDLQWLP----------------IAVPSCLDWYPYNYTLCPPHKPEN 298
            |:..:|...|.|...|...:.|.||                :|:      |||:..     .|::
  Rat    28 DRTIYVRDPTSNKQQRPVPESQLLPGQRFQAKDPEEQGDIVVAL------YPYDGI-----HPDD 81

  Fly   299 LTVTQKQYLPNIL--------ALNITWARPRYLPDNYTLHIFDL------FKGGTELNYTLDQNR 349
            |:..:.:.: .:|        |.:::..|..::|.||...:..|      ||..|.    .|..|
  Rat    82 LSFKKGEKM-KVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITR----KDAER 141

  Fly   350 SHFYVPKITVLGSHFEVHLVAQS---AGGKNVSGLTLDKVHRGVL-------LSEGNMVKLVLFI 404
                  ::...|:.....|:.:|   .|..::|....|.:|..|:       |..|.      :.
  Rat   142 ------QLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGG------YY 194

  Fly   405 IVP---ICCILMLC------SLTFCRRNRSEVQALQMDAKDAKASEFHLSLMDSSGLLVTLSANE 460
            |.|   ..||..:.      |...|||    ::...:..|..|..:
  Rat   195 ISPRITFPCISDMIKHYQKQSDGLCRR----LEKACISPKPQKPWD------------------- 236

  Fly   461 SLEVMDELEVEPHSVLLQDVLGEGAFGLVRRGVY-KKRQVAVKLLKDEPNDEDVYAFKCEIQMLK 524
                .|..|:...|:.|...||.|.||.|..|.| ...:||||.||  |......||..|..::|
  Rat   237 ----KDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLK--PGTMSAQAFLEEANLMK 295

  Fly   525 AVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRR 589
            .: :|..:|.:....|: ...:.::.|:.:.|||.:||
  Rat   296 TL-QHDKLVRLYAVVTK-EEPIYIITEFMAKGSLLDFL--------------------------- 331

  Fly   590 FNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGG 654
                                                                             
  Rat   332 ----------------------------------------------------------------- 331

  Fly   655 SYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLL 719
                                          |||...::...|                     |:
  Rat   332 ------------------------------KSDEGSKVLLPK---------------------LI 345

  Fly   720 DIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIK 784
            |.:.|:|.||.::.:...:||||.|.|||:|.....|||||||:| |..:|.|....|: |.|||
  Rat   346 DFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLAR-VIEDNEYTAREGA-KFPIK 408

  Fly   785 WLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMF 849
            |.|.|::....:|.:|||||||:|||||.|.|.:|||..:.:|::..|.||:||.|.|.|..|::
  Rat   409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELY 473

  Fly   850 SLMESCWSSVPSHRPTFSALKHRLGGMILAT 880
            .:|:.||......||||..|:..|.....||
  Rat   474 DIMKMCWKESAEERPTFDYLQSVLDDFYTAT 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	102/394 (26%)
Lyn	NP_110484.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		5/21 (24%)
		SH3_Lyn	67..122	CDD:212937	12/66 (18%)
		SH2_Src_Lyn	125..225	CDD:198227	23/119 (19%)
		PTKc_Lyn	239..510	CDD:270657	108/415 (26%)