Protein Alignment tor and kdrl

DIOPT Version :9

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_571547.1
• Gene: kdrl / 796537
• ZFINID: ZDB-GENE-000705-1
• Length: 1301
• Species: Danio rerio
• Alignment Length: 898
• Identity: 222/898 - (24%)
• Similarity: 343/898 - (38%)
• Gaps: 285/898 - (31%)

  Fly   102 TEPAPNATYIIRVD-----AVKDDNKETALYLSDDNFLILPGLESNSTHNITALAM---HGDGSY 158
            |:|.|    |..||     .:||.|.:.             ||..:....|:.|.:   :..|.|
Zfish   474 TDPLP----IENVDDFPQNPIKDVNSKV-------------GLLKSKNRTISTLVVKTANVSGVY 521

  Fly   159 SLIAKDQTFATLIRGYQPSKMGAVNLLRFVPQPDDLHHIAAEIEWKPSA---------------- 207
            |..|:::.....:|               :|...|.|....|||  ||.
Zfish   522 SCTARNELGNRTMR---------------IPFYVDDHPQPFEIE--PSTAVAGDDITLTCRGTRY 569

  Fly   208 --ESNCYFDMVSYSTNSVNMDE----------PLEVQFRDRKKLYRHTVD------NLEFDKQYH 254
              :...::|.:.|   .|..||          .|.::..:..:  .||:.      |:..:|
Zfish   570 LYDRLTWYDPLGY---KVPKDETTLRIEPYTISLSIKLPNVSR--NHTLGYECQALNINTNK--- 626

  Fly   255 VGVRTVNIMNRLESDLQWLPIAVPSCLDWYPYNYTLCPPHKPENLTVTQKQYLPNILALNITWAR 319
                .||:.:.|..|.:..|        |...|.|....:....||:....|  .:.|..|||.:
Zfish   627 ----VVNVTSALTIDERQGP--------WLMQNLTNQDVNSSSTLTLACLAY--GVPAPFITWYK 677

  Fly   320 PR---------YLPDNYTLHIFDLFK---GGTELNYTLDQNRSHFYVPKITVLGSHFEVHLVAQS 372
            .:         .|.|:.||.|..:.|   |..|...:.|...:.... .|||:|..
Zfish   678 DKTPVTEGPGITLKDDGTLIIERVKKDDEGIYECRASNDGGEAKTSA-VITVVGED--------- 732

  Fly   373 AGGKNVSGLTLDKVHRGVLLSEGN-----MVKLVLFIIVPICCILMLCSLTFCRRNRSEVQALQM 432
             |..|:..:        :|:|.|.     .:.|:|||                |:.|....|
Zfish   733 -GKPNIEVI--------ILVSTGAAATFLWIMLILFI----------------RKLRKPSSA--- 769

  Fly   433 DAKDAKASEFHLSLMDSSGLLVTLSANESLEVMDELEVEPHS----------VLLQDVLGEGAFG 487
               |.|           :|.|..:...|.:.:.::.:..|:.          :.|...||.||||
Zfish   770 ---DLK-----------TGYLSIIMDPEQMPLDEQCDRLPYDSNKWEFPQDRLRLGKTLGHGAFG 820

  Fly   488 LVRR----GVYK---KRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSNQ 545
            .|..    |:.|   .:.||||:||....:.:..|...|:::|..:|.|.|:|.::|..|:....
Zfish   821 KVVEASAFGIDKISTCKTVAVKMLKVGATNNEWRALMSELKILIHIGHHLNVVNLLGACTKRGGP 885

  Fly   546 MMLLIEYCSLGSLQNFLRE---EWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINN 607
            :|:::|:|..|:|.|:||.   ::...:.|:...::.
Zfish   886 LMIIVEFCKYGNLSNYLRSKRGDFVVYKSQDGKAVRS---------------------------- 922

  Fly   608 SMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKL 672
                            ||.|:...|.:         ..||.:.:.|.|
Zfish   923 ----------------SSGCDLSELIK---------RRLESVASTGSS----------------- 945

  Fly   673 KPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRI---PLKYADLLDIAQQVAVGMEFLAQ 734
                   :...|        .|:|.|.|..:..:.:..:   .|...||:..:.|||.||||||.
Zfish   946 -------ASSGF--------IEDKSYCDSEEEEEEQEDLYKKVLTLEDLICYSFQVAKGMEFLAS 995

  Fly   735 NKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVY-RKSGGSGKLPIKWLALESLTHQVYTS 798
            .|.:||||||||:|:|.:..:||.||||:||||.:..| ||  |..:||:||:|.|::..::||:
Zfish   996 RKCIHRDLAARNILLSENNVVKICDFGLARDVYKDPDYVRK--GDARLPLKWMAPEAIFDKIYTT 1058

  Fly   799 QSDVWSFGVLLYEITTLGGMPYPSVS-PSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSH 862
            ||||||||||::||.:||..|||.:. ..:....|::|.|||.||..:.|::..|..||...||.
Zfish  1059 QSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQ 1123

  Fly   863 RPTFSALKHRLGGMILATNDVPERLKQLQAATESKLKSCDGLNSKVEQVPCEE 915
            ||||:.|..|||.::.|:  |.:..|.......:.|...|..|    |.|.||
Zfish  1124 RPTFTELVERLGDLLQAS--VQQEGKHYIPINTALLTKADPSN----QSPTEE 1170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	FN3	199..261	CDD:214495	15/95 (16%)
		STYKc	475..873	CDD:214568	127/412 (31%)
		PTKc	479..873	CDD:270623	126/408 (31%)
kdrl	NP_571547.1	IG_like	47..120	CDD:214653
		IG_like	228..319	CDD:214653
		Ig	236..321	CDD:299845
		IG_like	338..415	CDD:214653
		Ig	343..415	CDD:299845
		Ig	441..533	CDD:143165	17/75 (23%)
		IG_like	553..631	CDD:214653	12/89 (13%)
		I-set	646..728	CDD:254352	19/84 (23%)
		Ig	659..725	CDD:143165	16/68 (24%)
		PKc_like	800..1141	CDD:304357	130/427 (30%)
		Pkinase_Tyr	808..1134	CDD:285015	127/412 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1158..1178		6/17 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1265..1291

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910