Protein Alignment tor and flt3

DIOPT Version :9

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_001921760.3
• Gene: flt3 / 566708
• ZFINID: ZDB-GENE-050114-4
• Length: 956
• Species: Danio rerio
• Alignment Length: 913
• Identity: 220/913 - (24%)
• Similarity: 377/913 - (41%)
• Gaps: 282/913 - (30%)

  Fly    83 CRTESEIVFQIDWVQHSRGTE-PAPNA-----TYIIRVDAVKDDNKETA---LYLSDDNFLIL-- 136
            |:|||.::....::..:...: .|.||     |.:...| :.:.||:.:   :||.....|:|
Zfish   170 CKTESTLISYYSYLSKNPNQKCCASNALGEECTEVYHYD-LNEKNKQKSQNIIYLKSGQSLLLRA 233

  Fly   137 -------PGLE--SNST--HNITALA--------------MHGDGSYSLIAKDQT---FATLIRG 173
                   ||::  .|:|  ..||:|.              |...|.|...:..:|   .:|.::.
Zfish   234 ARKHFKNPGIKWHFNNTVIKGITSLQFYDWTEHLFIESVNMAHSGLYLCTSDTETPRNCSTHVKV 298

  Fly   174 YQPSKMGAVNLLRFVPQPDDLHHIAA----------EIEWKPSAESNCYFDMVSYSTNSVNMDEP 228
            ::..::..::|       ::.:.|.|          ::...|.|  .||:  ::.:...:..||.
Zfish   299 FEHDQIDILHL-------NENNSILAKNKTGFCFQSQVFSYPKA--RCYW--ITPNQTQIQCDET 352

  Fly   229 LEVQFRDRKKLYRHTVDNLEFDKQYHVGVRT--VNIMNRLE---SDLQWLPIAVPSCLDWYPYNY 288
            .:..|....||.     |.| ..||.:.:.|  .::|..:.   ||:..:.|...|       ::
Zfish   353 SQSNFTSTFKLC-----NTE-PGQYQMKLETQEYSVMRNVSLCISDIPKITIRKNS-------SF 404

  Fly   289 TLCPPHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTELNYTLDQ----NR 349
            |.|....|..:||:.|. .|::...:         |:::.             ....||    :.
Zfish   405 TTCETESPLPVTVSWKT-CPSLAKCD---------PEDWK-------------EIAADQPEFTDS 446

  Fly   350 SHFYVPKITVLGSHF--EVHLVAQSAGGKNVSGL-TLDKVHRGVLLSEGNMVKLVLFIIVPICCI 411
            ..|...||.....|.  |.||:....  .||:|. ..:|:   :|.::.:...::.|:::.|..:
Zfish   447 DQFCQKKIGFSRRHLKSEDHLIKCCI--TNVAGTGCSEKI---LLQTKSHTYYVICFLLIVILFM 506

  Fly   412 LMLCSLTFCR----RNRSEVQALQM-----------DAKDAKAS---EFHLSLMDSSGLLVTLSA 458
            :::..:.|.|    :.:|::|.:||           |.::.|..   ||               .
Zfish   507 IIIALIIFIRVKKPKYQSQIQMIQMIGPNDNDYIYIDFREFKYDLKWEF---------------P 556

  Fly   459 NESLEVMDELEVEPHSVLLQDVLGEGAFGLVRR----GVYK---KRQVAVKLLKDEPNDEDVYAF 516
            .|:||:.:|             ||.||||:|.:    |:.|   ..|||||:||::....:..|.
Zfish   557 RENLELGNE-------------LGSGAFGMVVQATAYGISKPGVSVQVAVKMLKEKHQAVEKEAL 608

  Fly   517 KCEIQMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLR--------------EEWK 567
            ..|::||..:|.|.|||.::|..|. |..:.|:.::|..|.|.|:|:              .:.:
Zfish   609 MSELKMLTHIGHHENIVNLLGACTG-SGPIYLIFQFCCNGDLLNYLKSNRECFHKYLTDAFNKDR 672

  Fly   568 FRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSMLSTV----EEESESDQTHSSRCE 628
            ||      ||..|.:||          |||....:.| |:..|:..    |:|:|:|...||...
Zfish   673 FR------GLYHNFQQN----------RNSSEYVLSD-NSQCLNVTPASKEQENENDALLSSSIS 720

  Fly   629 TYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIF 693
            :                        ||        |.:
Zfish   721 S------------------------GS--------PAE--------------------------- 726

  Fly   694 ENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIA 758
               |..:|.|....:....|.|.|||..:.|||.||:||:....:||||||||||::..|.:|||
Zfish   727 ---EMLECEDEHQEEELHSLTYDDLLSFSFQVAKGMQFLSAKNCIHRDLAARNVLVTHGRQVKIA 788

  Fly   759 DFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSV 823
            ||||:||:.|::.| ...|:.:||:||:|.||:...:||.:||:|::|:||:||.:||..|||.|
Zfish   789 DFGLARDIEHDSNY-VVRGNVRLPVKWMAPESIFKGIYTMESDIWAYGILLWEIFSLGVTPYPGV 852

  Fly   824 SPSD-LLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFS-----------ALKHRL--- 873
            :.:: ..:::..|:.:::|....:.::.:|..||:..|..||.||           ||:.||
Zfish   853 TVNNTFYRMIESGYHLEQPYYAAESVYKVMCRCWALNPVDRPCFSKIVAFMEKELAALEERLYYN 917

  Fly   874 -GG 875
             ||
Zfish   918 VGG 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	FN3	199..261	CDD:214495	15/73 (21%)
		STYKc	475..873	CDD:214568	129/434 (30%)
		PTKc	479..873	CDD:270623	129/430 (30%)
flt3	XP_001921760.3	IGc2	225..283	CDD:197706	12/57 (21%)
		PKc_like	522..907	CDD:328722	139/493 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010