Protein Alignment tor and Ret

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 150/539 - (27%)
• Similarity: 222/539 - (41%)
• Gaps: 181/539 - (33%)

  Fly   374 GGKNVSGLTLDKVHRGVLLSEGNMVKLVLFIIV-PICCILMLCSLTFCRR----NRSEVQALQMD 433
            |..||:|...|:             ..:.|:|. |:..:|:|..|...:|    .|...|::...
  Fly   682 GVLNVAGFECDR-------------SCMFFVITCPLLFVLLLLCLLIAQRKMLQRRLGKQSMTTS 733

  Fly   434 AKDAKASEFHLSLMDSSG---LLVTLSANESLEVMD-ELEVEPHSVLLQDVLGEGAFGLVRRGVY 494
            :|.|        |.:|.|   .|:.|.:....|..| :.|.....:.|..|||||.||.|.:|..
  Fly   734 SKQA--------LPESGGGDFALMPLQSGFRFESGDAKWEFPREKLQLDTVLGEGEFGQVLKGFA 790

  Fly   495 KK-------RQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEY 552
            .:       ..||||:||...|..:..|...|.|:|:.| .|||::.::|..|. |...:|:|||
  Fly   791 TEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEV-SHPNVIKLLGACTS-SEAPLLIIEY 853

  Fly   553 CSLGSLQNFLREEWKFRQEQNAIGLKKNLE-QNVDNRRFNRLPRNSIHDRIEDINNSMLSTVEEE 616
            ...|||:::||             |.:.:| ..||           ..|.:|.:|..|
  Fly   854 ARYGSLRSYLR-------------LSRKIECAGVD-----------FADGVEPVNVKM------- 887

  Fly   617 SESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKDSK 681
                                                                             
  Fly   888 ----------------------------------------------------------------- 887

  Fly   682 QDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARN 746
                                                :|..|.|:..||.:|::.|:|||||||||
  Fly   888 ------------------------------------VLTFAWQICKGMAYLSELKLVHRDLAARN 916

  Fly   747 VLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYE 811
            ||::..:..||:||||:||||.::.|.|. ...::|:||:|.|||...||||:|||||||||.:|
  Fly   917 VLLADGKICKISDFGLTRDVYEDDAYLKR-SRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWE 980

  Fly   812 ITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSALKHRLGGM 876
            :.|||..|||.::|.:|..||:.|:||.|||.|::.::|::.:||:..|:.||:|..|......:
  Fly   981 LITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKL 1045

  Fly   877 I--------LATNDVPERL 887
            :        |.||.|...|
  Fly  1046 LGNNAKYIDLETNAVSNPL 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	120/401 (30%)
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	121/413 (29%)