Protein Alignment tor and Drl-2

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_610835.2
• Gene: Drl-2 / 36436
• FlyBaseID: FBgn0033791
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 792
• Identity: 162/792 - (20%)
• Similarity: 265/792 - (33%)
• Gaps: 264/792 - (33%)

  Fly   166 TFATLIRGY--------QPSKM------------GAVN--LLRF-VPQPDDLHHIAAEIEWKPSA 207
            |.:|.:.||        :..|:            ||:|  .:.| ||.|.|:|.:  |..|:
  Fly    18 TISTSVSGYLNIFISHHEVMKLMGLEADLFYVHEGAINTYAMHFTVPVPADVHEL--EFSWQ--- 77

  Fly   208 ESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRHTVDNLEFDK-QYHVGVRTVNIMNR------ 265
                  .:::|         ||....            ::|::. |..:|..|::|.::
  Fly    78 ------SLIAY---------PLPYAI------------SIEYNNDQEALGTPTLSIPHKGLVPQE 115

  Fly   266 LESDLQWLPIAVPSCLDWYPYNYTLCPPHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLH 330
            :||.|.:||....:.|            ..|.|:.:             :..|.||:
  Fly   116 IESFLVYLPCTGNASL------------QMPVNVNM-------------VVRAPPRF-------- 147

  Fly   331 IFDLFKGGTELNYTLDQNRSHFYVPKITVLG-------SHFEVHLVAQSAGGKNVSGLTLDKVHR 388
                           :..|.||...||...|       |....|..:|.....:.:...|
  Fly   148 ---------------NDTRLHFKRNKICAKGISPEPNQSPAPAHAPSQGPALLSAAACAL----- 192

  Fly   389 GVLLSEGNMVKLVLFIIVPICCILMLCSLTFCRRNRSEVQALQMDAKDAKASEFHLSLM------ 447
            |::|:.|                 ::.|:.:.|..           |..:....|.|..
  Fly   193 GLVLAVG-----------------LVASMMYVRAR-----------KQLRQDSLHTSFTTAAYGS 229

  Fly   448 ---------------DSSGLLVTLS--------ANESLEVMDELEVEP-----HSVLLQDVLGEG 484
                           .::|...|::        :.:|..:.|.....|     .:.||...|.:.
  Fly   230 HQNVFIRLDPLGRPPSATGSYATIASLNKYPADSKKSCSIFDRFRSSPTPTPYATALLPMNLEQT 294

  Fly   485 AFGLVRRGVYKKRQVAVKLLKDEPNDEDVYAFK-----CEIQMLKAVGKHPNIVGIVGYSTRFSN 544
            |     ..:|.|.:...      |:....||..     |.:...|::..:.|     |..|..|.
  Fly   295 A-----ETIYSKPESIC------PSRISYYASSQLTQPCSLSTPKSIRSNGN-----GNCTSGSG 343

  Fly   545 QMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSM 609
            .:.|      .|.:..           .:.|.:..:.|:.  |:|..         ||..:....
  Fly   344 SLSL------FGGIPT-----------GSTITMASHGEKG--NQRLR---------RITSVQPGA 380

  Fly   610 LSTVE--EESESDQTHSSR----CETYTLTRITNAA-DNKGYGLEDIE-NIGGSY----IPKTAE 662
            ||..|  :|....:.::.:    ||....|.|..|: ......|:|.. .||.|:    .|..|.
  Fly   381 LSYEELVKEGTFGRIYAGKLGESCEALVKTVIDGASLTQVACLLQDASLLIGVSHQHILAPLLAN 445

  Fly   663 APKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAV 727
            .....|.....|.|.|.:.              |.|......|.|    .|....|::....:..
  Fly   446 TELPGPPEIAYPHPSKGNL--------------KMYLQKSRESST----ALSTRQLVEFGLHITK 492

  Fly   728 GMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLT 792
            |:.:|....:||:|:|.||..:..:..:||.|..||||::.:: |...|.:...|:|||:||||.
  Fly   493 GLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDD-YDCLGDNENRPLKWLSLESLQ 556

  Fly   793 HQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWS 857
            .:||.:|.|||:.||..:|:.||..||:..|...:|...|..|.|:::|..|..|.|::|..||.
  Fly   557 KRVYATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWH 621

  Fly   858 SVPSHRPTFSAL 869
            .....|||.|.|
  Fly   622 CEAKQRPTPSQL 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	102/408 (25%)
Drl-2	NP_610835.2	WIF	30..156	CDD:460414	34/205 (17%)
		PTK_Ryk	373..644	CDD:270639	82/280 (29%)