Protein Alignment tor and yrk

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001352482.1
• Gene: yrk / 337571
• ZFINID: ZDB-GENE-030131-9517
• Length: 528
• Species: Danio rerio
• Alignment Length: 673
• Identity: 151/673 - (22%)
• Similarity: 230/673 - (34%)
• Gaps: 266/673 - (39%)

  Fly   239 LYRH---TVDNLEFDK--QYHVGVRTVNIMNRLESDLQWLPIAVPSCLDWY-PYNYTLCPPHKPE 297
            ||.:   |.|:|.|.|  ::|       |:|..|.| .|...::.:....| |.||.     .|.
Zfish    81 LYEYDARTEDDLSFQKGEKFH-------IINNTEGD-WWEARSLDTGKSGYIPSNYV-----APV 132

  Fly   298 NLTVTQKQYL---------PNILALNITWARPR--YL-------PDNYTLHI--FDLFKGGTELN 342
            :....::.|.         ..:||.|    .||  :|       ...|:|.|  :|..||....:
Zfish   133 DSIQAEEWYFGKMGRKDAERQLLAQN----NPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKH 193

  Fly   343 YTLDQ-NRSHFYVPKITVLGSHFEV--HLVAQSAGGKNVSGLTLDKVHRGVLLSEGNMVKLVLFI 404
            |.:.: :...:|:...|...:..::  |...::||
Zfish   194 YKIRKLDNGGYYITTRTQFDTVQQLVEHYTERAAG------------------------------ 228

  Fly   405 IVPICCILMLCSLTFCRRNRSEVQALQMDAKDAKASEFHLSLMDSSGLLVTLSANESLEVMDELE 469
               :||.|    :..|||...::..|.:..||.                              .|
Zfish   229 ---LCCRL----IGSCRRGMPKLADLSVKTKDV------------------------------WE 256

  Fly   470 VEPHSVLLQDVLGEGAFGLVRRGVYK-KRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIV 533
            :...|:.|...||.|.||.|..|::. ..:||||.||  |......||..|.|::|.: :|..:|
Zfish   257 IPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLK--PGTMSPEAFLDEAQIMKRL-RHDKLV 318

  Fly   534 GIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSI 598
            .:  |:......:.::.|:.|.|||.:||
Zfish   319 QL--YAVVSEEPIYIITEFMSQGSLLDFL------------------------------------ 345

  Fly   599 HDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEA 663
                                                                             
Zfish   346 ----------------------------------------------------------------- 345

  Fly   664 PKDRPKRKLK-PQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAV 727
             ||...|.|| ||                                          |:|:|.|:|.
Zfish   346 -KDGDGRNLKLPQ------------------------------------------LVDMAAQIAA 367

  Fly   728 GMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLT 792
            ||.::.:...:||||.|.|:|:......|||||||:| :..:|.|....|: |.||||.|.|:..
Zfish   368 GMAYIERMNYIHRDLRAANILVGDGLVCKIADFGLAR-LIEDNEYTARQGA-KFPIKWTAPEAAL 430

  Fly   793 HQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWS 857
            :..:|.:|||||||:||.|:.|.|.:|||.::..::|:.:.:|:||..|:|....:..||..||.
Zfish   431 YGKFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCPQGSPASLHELMLQCWR 495

  Fly   858 SVPSHRPTFSALKHRLGGMILAT 880
            ..|..|.||..|:..|.....||
Zfish   496 KDPDERHTFEYLQSFLEDYFTAT 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	99/395 (25%)
yrk	NP_001352482.1	SH3	76..133	CDD:473055	18/64 (28%)
		SH2	136..234	CDD:472789	22/138 (16%)
		PTKc_Src_Fyn_like	266..513	CDD:271105	100/397 (25%)