Protein Alignment tor and Ddr

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Alignment Length: 680
• Identity: 147/680 - (21%)
• Similarity: 246/680 - (36%)
• Gaps: 178/680 - (26%)

  Fly   322 YLPDNYTLHIFDLFKGGTELNYTLDQN-RSHFY-------VPKITVLGSHFEVHLVAQSAGGKNV 378
            |:||....|..|:   ..:|::.|.:. :.|.|       :.:||.:.:....:...:.|.|:..
  Fly   395 YMPDLVLDHARDV---TIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVGNFTDELANGEKQ 456

  Fly   379 S-----GLTLDKVHRGV------------LLS---------EGNMVKLVLFIIVPICCILMLCSL 417
            |     .|..|:|.|.:            ::|         |.:.|.:::.::..|..:|:...|
  Fly   457 SVTSEYPLQRDEVGRAISSGGERSQHTTQVISPKPIDHQEPETSFVGVIITVLGTIIMLLVAFIL 521

  Fly   418 TFCRRN---RSEVQALQMDAKDAKASEFHLSLMDSSGLL---VTLSANESLEVMDELEVEPHSVL 476
            ....||   ||....|     ||....|....::.:|:|   .|:..|||....:.|..||.:..
  Fly   522 LIVARNKHVRSRENGL-----DAFQHNFSPDTLNGNGVLKVVTTMDDNESSIDKNSLYHEPFNAN 581

  Fly   477 LQDVLGEGAFGLVRRGVYKKRQVAVKLLKDEPNDEDVYAFKCE------IQML------------ 523
            :.    ..|.........:::.|:       |:..||....|:      :|.|
  Fly   582 MY----TSAASACPMNDLQRQHVS-------PDYTDVPDIVCQDYAVPHMQQLLPNAPPCGSGCG 635

  Fly   524 ------KAVGKHPNIV---GIVGYSTRFS-NQMML----------LIEYC--------------- 553
                  ...|..|..|   |.|..|.|.| |...|          |.:|.
  Fly   636 TGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLPLPSPPVPPPLEKYYAATPVSSKPMPVAPP 700

  Fly   554 ---SLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVD-NRRFNRLPRNSIHDRIEDINNSMLSTVE 614
               |.|||.:....  ........:|:.|....|:| :..|..:.....:.::::.....|..||
  Fly   701 GSQSSGSLSSSTTA--ATTPTSGVVGVGKPHHYNLDMSANFADINEERANCQVQEFPRQSLVIVE 763

  Fly   615 EESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKD 679
            :...........|||..|.....|......|..|                      .|:.:.:..
  Fly   764 KLGSGVFGELHLCETNVLNATLVAVATLRPGAND----------------------HLRKEFRSK 806

  Fly   680 SKQ--DFKSDNKKRIFEN----------KEYFDCL------------DSSDTKPRIPLKYADLLD 720
            :||  .....|..|:...          ::|..||            ::|....:..|.:..|:.
  Fly   807 AKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQEHVAETSGLMAKKSLSFGCLVY 871

  Fly   721 IAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFG--LSRDVYHENVYRKSGGSGK--- 780
            ||.|:|.||:.|.|...||||||.|:.:|..:..:|:...|  ::|..|..:..:..|.:|:
  Fly   872 IATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGFTGRQSQ 936

  Fly   781 -LPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLG-GMPYPSVSPSDLLQ---LLRQGHRMKR 840
             :||:|:|.||:....:|::||||||.|.|:||.|.. ..||..:|...:::   |:.:.::|..
  Fly   937 PMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHE 1001

  Fly   841 ----PEGCTQEMFSLMESCWSSVPSHRPTF 866
                |..|.:|::.||..||....|.||:|
  Fly  1002 LLPMPPNCPREIYDLMCECWQRDESSRPSF 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	106/483 (22%)
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014
		PTKc_DDR	753..1040	CDD:270644	77/301 (26%)