Protein Alignment tor and src

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_017209008.1
• Gene: src / 325084
• ZFINID: ZDB-GENE-030131-3809
• Length: 549
• Species: Danio rerio
• Alignment Length: 733
• Identity: 160/733 - (21%)
• Similarity: 241/733 - (32%)
• Gaps: 285/733 - (38%)

  Fly   172 RGYQPSKMGAVNLLRFVPQPDDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPLEV----- 231
            ||.||:.:.|...|                           |..|:.:|||:.....:.:
Zfish    48 RGTQPNIINAEQAL---------------------------FGGVNSTTNSITSPNRIGILGGVT 85

  Fly   232 ------QFRDRKKLYRHTVDNLEFDKQYHVGVRTVNIMNRLESDLQWLPIAVPSCLDWYPYNYTL 290
                  .:..|      |..:|.|.|...:.:  ||...:|.          |...||:
Zfish    86 TFVALYDYESR------TASDLSFRKGERLQI--VNNTRKLN----------PREGDWW------ 126

  Fly   291 CPPHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTELNYTLDQNRSHFYVP 355
                                ||.::|.....|:|.||... .|..:....|..||::   .:|..
Zfish   127 --------------------LARSLTTGESGYIPSNYVAP-SDSIQAEDHLRLTLEK---RWYFG 167

  Fly   356 KITVLGSH------------FEVHLVAQSAGGKNVSGLTLDKVHRGVLLSEGNMVKLVLFIIVPI 408
            |||...|.            |.|.....:.|...:|.|..|.| :|:.:....:.|
Zfish   168 KITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDYDNV-KGLNVKHYKIRK--------- 222

  Fly   409 CCILMLCSLTFCRRNRSEVQALQMDAKDAK--ASEFHLSLMD--------SSGLLVTLSANESLE 463
                 |.|..|...:|::...||......:  |.....||.|        :.||
Zfish   223 -----LDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCPVLKPPTQGL----------- 271

  Fly   464 VMDELEVEPHSVLLQDVLGEGAFGLVRRGVYK-KRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVG 527
            ..|..|:...|:.|...||:|.||.|..|.:. ..:||:|.||  |......||..|.|::|.:
Zfish   272 ARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLK--PGTMSPEAFLQEAQVMKKL- 333

  Fly   528 KHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNR 592
            :|..:|.:  |:......:.::.||...|||.:||:.                     |..:..|
Zfish   334 RHEKLVQL--YAVVSEEPIYIVTEYMGQGSLLDFLKG---------------------DMGKMLR 375

  Fly   593 LPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYI 657
            ||:
Zfish   376 LPQ-------------------------------------------------------------- 378

  Fly   658 PKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIA 722
                                                                        |:|:|
Zfish   379 ------------------------------------------------------------LVDMA 383

  Fly   723 QQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLA 787
            .|:|.||.::.:...|||||.|.|:|:..:...|:|||||:| :..:|.|....|: |.||||.|
Zfish   384 SQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLAR-LIEDNEYTARQGA-KFPIKWTA 446

  Fly   788 LESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLM 852
            .|:..:..:|.:|||||||:||.|:||.|.:|||.:...::|..:.:|:||..|..|...:..||
Zfish   447 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELM 511

  Fly   853 ESCWSSVPSHRPTFSALK 870
            .:||...|..||||..|:
Zfish   512 LTCWRKEPEERPTFEYLQ 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	97/393 (25%)
src	XP_017209008.1	SH3	85..148	CDD:473055	18/107 (17%)
		SH2_Src_Src	162..260	CDD:198228	23/115 (20%)
		PTKc_Src	273..549	CDD:270656	101/407 (25%)