Protein Alignment tor and Pdgfra

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_038947553.2
• Gene: Pdgfra / 25267
• RGDID: 3284
• Length: 1111
• Species: Rattus norvegicus
• Alignment Length: 1115
• Identity: 243/1115 - (21%)
• Similarity: 389/1115 - (34%)
• Gaps: 409/1115 - (36%)

  Fly    83 CRTESEIVFQIDWVQHSRGTEPAPNATYIIRVDAVKDDNKETALYLSDDNFLILPGLESNSTHNI 147
            |..|||    :.| ||....|..||.       .::.:...::|:::     :|..:.:::.|.
  Rat    71 CFGESE----VSW-QHPMSEEEDPNV-------EIRTEENNSSLFVT-----VLEVVNASAAHT- 117

  Fly   148 TALAMHGDGSYSLIAK-DQTFATLIRGYQPSKMGAVNLLRFVPQPD------DLHHIAAEIEWKP 205
                    |.|:.... .||        :.|::...::..:||.||      .:......:|...
  Rat   118 --------GWYTCYYNHTQT--------EESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDD 166

  Fly   206 SAESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRHTVD------------------------- 245
            ||...|.           ..|...||...:..:|...:.|
  Rat   167 SAIIPCR-----------TTDPDTEVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVRGRTF 220

  Fly   246 ----------------NLEFDKQ---YHVG---VRTVNIMNRLESDLQWL--------------P 274
                            |||.|.:   |..|   |.|..:.|....||||.              .
  Rat   221 KTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEE 285

  Fly   275 IAVPSCLDWYPYNYTLCPPH-----------------------KPENLTVTQKQYLP------NI 310
            |.:||    ....|||..|.                       |...::|.:|.::.      ::
  Rat   286 IKLPS----IKLVYTLTVPKATVKDSGDYECAARQATKEVKEMKTVTISVHEKGFVQIRPTFGHL 346

  Fly   311 LALNITWAR-----------PR--YLPDNYTLHIFDLFKGGTELNYTLDQNRSHFYVPKITVL-- 360
            ..:|:...|           ||  :|.||.|     |.:..||:...:.:::...|..|:.::
  Rat   347 ETVNLHQVREFVVEVQAYPTPRISWLKDNLT-----LIENLTEITTDVQRSQETRYQSKLKLIRA 406

  Fly   361 ----GSHFEV------------------------HLVAQ---SAGGK------------------ 376
                ..|:.:                        .||..   |.||:
  Rat   407 KEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELVDDHHGSGGGQTVRCTAEGTPLPNIEWMI 471

  Fly   377 ------------------NVSGLTLDKVHRG---------------------------------- 389
                              |||.:..:...||
  Rat   472 CKDIKKCNNDTSWTVLASNVSNIITEFHQRGRSTVEGRVSFAKVEETIAVRCLAKNDLGIGNREL 536

  Fly   390 -----VLLSEGNMVKLVLFIIVPICCILMLCSLTFCRRNRSEVQALQMDAKDAKASEF-HLSLMD 448
                 .|.||..:...||.::|.:...|::..:.:.::.|.|::...:::......|: ::..|
  Rat   537 KLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPM- 600

  Fly   449 SSGLLVTLSANESLEVMDELEVEPHSVLLQDVLGEGAFGLVRRGV-------YKKRQVAVKLLKD 506
                        .|......|.....::|..:||.||||.|..|.       ....:||||:||.
  Rat   601 ------------QLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKP 653

  Fly   507 EPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQE 571
            .....:..|...|::::..:|.|.|||.::|..|: |..:.::.|||..|.|.|:|.:
  Rat   654 TARSSEKQALMSELKIMTHLGPHLNIVNLLGACTK-SGPIYIITEYCFYGDLVNYLHK------- 710

  Fly   572 QNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRIT 636
                               ||              :|.:|...|:.:.|      .:.:.|
  Rat   711 -------------------NR--------------DSFMSRHPEKPKKD------LDIFGL---- 732

  Fly   637 NAAD--NKGYGLEDIENIGGSYIP-KTAEAPKDRPKRKLKPQPK----KDSKQDFKSDNKKRIFE 694
            |.||  .:.|.:...|| .|.|:. |.|:..:..|..:.|...|    :.|..|..:..||:...
  Rat   733 NPADESTRSYVILSFEN-NGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSML 796

  Fly   695 NKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIAD 759
            :.|..:.|...|::   .|...|||....|||.||||||....|||||||||||::..:.:||.|
  Rat   797 DSEAKNLLSDDDSE---GLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICD 858

  Fly   760 FGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVS 824
            |||:||:.|::.| .|.||..||:||:|.||:...:||:.|||||:||||:||.:|||.|||.:.
  Rat   859 FGLARDIMHDSNY-VSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMM 922

  Fly   825 -PSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSALKHRLGGMILATNDVPERLK 888
             .|.....::.|:||.:|:..|.|::.:|..||:|.|..||:|..|..      :..|.:|.:.|
  Rat   923 VDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSE------IVENLLPGQYK 981

  Fly   889 Q-------------------------------LQAATESKLKSCD-GLNSK-------------- 907
            :                               .....|.|||..: ||:.:
  Rat   982 KSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIPLPD 1046

  Fly   908 VEQVPCEEEL 917
            ::.||.||:|
  Rat  1047 IDPVPEEEDL 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	137/408 (34%)
Pdgfra	XP_038947553.2	None