DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tor and F59F5.3

DIOPT Version :9

Sequence 1:	NP_476762.1	Gene:	tor / 35717	FlyBaseID:	FBgn0003733	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_509765.2	Gene:	F59F5.3 / 186634	WormBaseID:	WBGene00010342	Length:	681	Species:	Caenorhabditis elegans

Alignment Length:	361	Identity:	89/361 - (24%)
Similarity:	141/361 - (39%)	Gaps:	91/361 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   577 LKKNLEQNVDNRRFNRLPRNSIHD-RIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAAD 640
            |.|:|.||    .:|::....:.: |||::||        :|:....:||...|..:.:......
Worm   339 LTKSLRQN----NYNKVSTTDVRETRIEELNN--------KSKLGVGNSSTIYTAEICKTKKCIV 391

  Fly   641 NKGYGLEDIENIGGSYIPKTAEAPKD--------------RPKRK-----------LKPQPKKDS 680
            .|       |::..|:..|..:..|.              :|::|           |.|..:|..
Worm   392 IK-------ESVRKSHCTKELKLLKSLKHPNIITPLGVIVQPEQKTCFNVQIRQHLLLPYYQKTC 449

  Fly   681 KQDF--KSDNKKR----IFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVH 739
            .:.:  |....||    ||...|        .|.|...:...||:.||.|||..:|:|...::.|
Worm   450 LETYIHKFYPPKRGGNNIFHTNE--------ATVPEEEITMFDLVSIAWQVASALEYLKGMEITH 506

  Fly   740 RDLAARNVLISVDRSIKIADF------GLSRDVYHENVYR---KSGGSGKLPIKWLALESLTHQV 795
            ||:|.||||||.::..||.||      ..:|.:..|...:   |:..|..:| |....|.|....
Worm   507 RDVAMRNVLISNNKVCKITDFERAKKGETTRKISIEKKIKEILKAHMSKDIP-KEYPNECLKGVY 570

  Fly   796 YTSQSDVWSFGVLLYEITTL-----GGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESC 855
            |...|:|:.||.|:..:.:.     .|..||.:                :||.|.:.::.|:..|
Worm   571 YYYSSEVYCFGRLMLCLFSFMKPCDYGRIYPPI----------------QPENCPKAIYDLIVDC 619

  Fly   856 WSSVPSHRPTFSALKHRLGGMILATNDVPERLKQLQ 891
            .:.....||:.|:.|..| ..:|...|..|.||..|
Worm   620 INENRKSRPSISSCKDVL-STVLKHMDHDEFLKLKQ 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	FN3	199..261	CDD:214495
		STYKc	475..873	CDD:214568	82/341 (24%)
		PTKc	479..873	CDD:270623	82/341 (24%)
F59F5.3	NP_509765.2	Pkinase_Tyr	<413..637	CDD:369480	62/248 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100