Protein Alignment tor and F09A5.2

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001360730.1
• Gene: F09A5.2 / 181440
• WormBaseID: WBGene00008599
• Length: 867
• Species: Caenorhabditis elegans
• Alignment Length: 842
• Identity: 177/842 - (21%)
• Similarity: 306/842 - (36%)
• Gaps: 309/842 - (36%)

  Fly   144 THNITALAMHGDGSYSLIAKDQTFATLIRGYQPSKMGAVNLLRFV-----------------PQP 191
            |.||:...:.|..|.:......|.|.:::..........::|.||                 ||.
 Worm   119 TGNISDACLAGIKSSNCKTWLMTNAVILKYSDDVVSNCPSILEFVNKTSLSCSGKSQIQYMYPQS 183

  Fly   192 DDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRHTVDNLEFDKQYHVG 256
            |             ||.|:|..   ||..||..::..: ..|...|.|...:..|......|...
 Worm   184 D-------------SASSDCNH---SYDFNSNALNRAI-YNFNYSKTLISTSYANTPGFAMYTFL 231

  Fly   257 VRTVNIMNR-----------LESDLQWLPI--------AVPSCLD----------WYPYNYTLCP 292
            ::.:|.:|:           :.:|:.::.:        :.|..|:          :|..|
 Worm   232 LKIMNCVNKNGIKLDAGILNIFTDMTYIDLCESDVFMSSFPDTLNKLIEAGYIVKFYFLN----- 291

  Fly   293 PHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTELNYTLDQNRSHFYVPKI 357
                :||..|||. :.|:|      |..:|:.......|.|       .:|       |...|
 Worm   292 ----QNLQDTQKN-VENVL------AGCKYMNSRSYCEIVD-------WSY-------HSENP-- 329

  Fly   358 TVLGSHFEVHLVAQSAGGKNVSGLTLDKVHRGVLLSEGNMVKLVLFIIVP-----ICCILMLCSL 417
                :.||:.:......||...             ...::.:|:|.|.:|     ||||......
 Worm   330 ----NEFEICIPDSQPSGKKED-------------FNWHVTELLLIIGIPCISLTICCIAFFVCC 377

  Fly   418 TFCRRNRSEVQALQMDAKDAKASEFHLSLMD-------------SSGLLVTL---------SANE 460
            ..|.:.:..:..:.:.:.|...:...:.|..             .:|....|         |||.
 Worm   378 LKCAKLKMAMMRMNVFSNDTHQNPDEMELKKRWIGMRKKFNKDVENGSCKELNTQKWSHFASANN 442

  Fly   461 SLEVM--------DELEVEPHSVLLQD--VLGEGAFGLVRRGVYKKR------------------ 497
            .:::.        |..|::..::|:|:  :||.|||..|.:|:.|.:
 Worm   443 YMDIQALANANKKDIWEIDTKNLLVQEDHLLGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESEN 507

  Fly   498 ----QVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSN--QMMLLIEYCSLG 556
                :.|:|.|....::::...|..||..:|.:|.||:::.::|.   .||  :.::::|||:.|
 Worm   508 NGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGC---VSNPYEPLIVVEYCARG 569

  Fly   557 SLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQ 621
            .|..|||
 Worm   570 DLLKFLR---------------------------------------------------------- 576

  Fly   622 THSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKS 686
                |.:.|.|...|:
 Worm   577 ----RHKDYVLMNKTD------------------------------------------------- 588

  Fly   687 DNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISV 751
                         ||...:|    :.|:..||:.||.|||.||.:||....:||||||||:|::.
 Worm   589 -------------DCPIEAD----MCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTK 636

  Fly   752 DRSIKIADFGLSRDVYHEN-VYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTL 815
            ..:.|::||||.|  |.:: :|...|  |:|||||:::|:|....:::::|||||||||:||.::
 Worm   637 SLTAKVSDFGLCR--YMDSALYTAKG--GRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSM 697

  Fly   816 GGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSALKHRLGGMI 877
            |.:|||::...|:|:.|..|.|:.:|..|..|:|::|:.||:..|..||.|:.::..:..|:
 Worm   698 GDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEITVML 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	105/420 (25%)
F09A5.2	NP_001360730.1	PTKc	473..752	CDD:270623	105/413 (25%)