Protein Alignment tor and hir-1

DIOPT Version :9

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_504458.1
• Gene: hir-1 / 178936
• WormBaseID: WBGene00016059
• Length: 903
• Species: Caenorhabditis elegans
• Alignment Length: 1019
• Identity: 230/1019 - (22%)
• Similarity: 360/1019 - (35%)
• Gaps: 356/1019 - (34%)

  Fly    32 DKTLLNVTACTQNCLE---KGQMDFRSCLKDCRING------TFPGALRKVQENYQMNMICRTES 87
            |.|..::.||...|.:   |......:|...|  ||      |.|.......:.
 Worm    43 DSTQQSLDACKPQCQKLNNKNLCSDNTCWSTC--NGELVPEKTLPAPTNLTLKG----------- 94

  Fly    88 EIVFQIDWVQHSRGTEPAPNAT-YIIRVDAVKDDNKETALYLSDDNFLI----------LPGLES 141
              |..:.|       .|.|.|. |.|   ..:..|.:|  :.||| |:|          |..::.
 Worm    95 --VRGLSW-------SPVPGAVMYYI---GYRTLNSKT--FTSDD-FVITEKQTVDLSTLTNIDP 144

  Fly   142 NSTHNITALAMHGDG-------------------SYSLIAKDQTFATLIRGYQPSKMGAVNLLRF 187
            .|...:...|...||                   ...|:.......||:..:..:........|:
 Worm   145 CSELEVAVAAFSEDGIGNESKELKISSPKPTANPKLDLLELQYLNTTLVSDFYQANATVHVEFRY 209

  Fly   188 VPQ-----PDD-----LHHIAAEIEWKPSAESNC---YFDM-VSYSTNSVNMDEPLEVQFRDRKK 238
            ...     |||     |.|:.:.::  |......   .||: |..||.|.::...:    .|||.
 Worm   210 KTDPWFLGPDDLDVQPLFHLISCVD--PDLSQGIPVPDFDVHVKNSTISTSIGSDM----MDRKC 268

  Fly   239 LYRHTVDNLEFDKQYHVGVRTVNIMNRL----ESDLQWLP-----------IAVPSCLDWYPYNY 288
            .|.:.:.::...|        .|.|..:    .|.||.:.           :.|||      |..
 Worm   269 RYVYYLQSVMSKK--------CNTMTEMPSPPSSALQTIQVECDIVKNAPCVKVPS------YQP 319

  Fly   289 TLCP----------PHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTELNY 343
            .||.          ....|||.........|:..:.:|  |...:|..|.:.||     ||...|
 Worm   320 PLCGMVENVAFSVLSRDRENLNDPASNLTVNVTFIPVT--RNNEMPTLYYIGIF-----GTASEY 377

  Fly   344 TLDQNRSHFYVPKITVLG----------------SHFEVHLVAQSAGGKNVSGL----------- 381
            ...:..:...|....|:|                .:....:|.|....|.:.||
 Worm   378 HTKEEETFLGVNITHVIGKESSCTGFDSSGNCLAENLNRSIVLQGIHPKTLYGLTICAVKDIRNL 442

  Fly   382 -----TLD------KVHRGVLL--SEGNMVKLVLFIIVPICCILMLCSLT--FCRRNRSEVQALQ 431
                 |||      |..|.:|:  :..|.|.:::.|::....::::..:.  |..|.:||    .
 Worm   443 TLPDVTLDSKSFRAKADRIMLVAHTSNNPVGMIIGIVIGSLVVILVAIVVIWFYFRKKSE----N 503

  Fly   432 MDAKDAKASEFHLSLMDSSGLLVTLSANESLE--VM----DELEVEPHSVLLQD--VLGEGAFGL 488
            |..|      |.:..:..:.:      |..::  :|    |..|:|..::::.:  .||.||||.
 Worm   504 MKFK------FQMEQVGKNNM------NRYIDFPIMAAKNDIWEIERRNLIIHNDKKLGSGAFGA 556

  Fly   489 VRRG-------VYKKR--------------QVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNI 532
            |..|       .:|..              |||||:|.:..::...:.|..||.::|.:|.|..:
 Worm   557 VYLGKLIGKSLAHKDANSPLGINLMRAENCQVAVKMLPEYADEMSKHEFLREIALMKTLGYHERL 621

  Fly   533 VGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNS 597
            |.::...|. |..:.|::|||..|.|..||||..|:..:.:.:|:                   :
 Worm   622 VNMLACVTE-SEPLCLVVEYCDNGDLLKFLRERCKYMMKLDDLGI-------------------N 666

  Fly   598 IHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAE 662
            .||
 Worm   667 YHD-------------------------------------------------------------- 669

  Fly   663 APKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAV 727
                         |.                ||:.|       ||...:.||  .||..|.|::.
 Worm   670 -------------PP----------------ENENY-------DTNMIVTLK--QLLQFAVQISY 696

  Fly   728 GMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLT 792
            |:|:|:|...||||:||||||:....:.||.||||.|.:|.:....||.| ||||:||::.|::.
 Worm   697 GLEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQSQYKSKG-GKLPLKWMSPEAIR 760

  Fly   793 HQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWS 857
            |..::.:||:||||:||:|:.||||.|||.:.|.|:|..|..|.|:::|:.|.:..:.:|..||:
 Worm   761 HYEFSIKSDIWSFGILLFEVITLGGSPYPGMPPEDVLPFLEGGGRIEKPDNCPENFYDVMMQCWN 825

  Fly   858 SVPSHRPTFSALKHRLGGMILATNDVPERLKQLQAATE--SKLK 899
            :.|..|..||.::     |.|||        ||:..||  |.||
 Worm   826 ADPDDRIEFSDVR-----MQLAT--------QLEDITEDYSYLK 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	FN3	199..261	CDD:214495	12/65 (18%)
		STYKc	475..873	CDD:214568	114/420 (27%)
		PTKc	479..873	CDD:270623	114/416 (27%)
hir-1	NP_504458.1	fn3	85..163	CDD:365830	20/103 (19%)
		PTKc	547..842	CDD:270623	115/420 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D256695at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920