Protein Alignment tor and si:ch73-40a2.1

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_009301289.1
• Gene: si:ch73-40a2.1 / 101885322
• ZFINID: ZDB-GENE-160728-89
• Length: 746
• Species: Danio rerio
• Alignment Length: 848
• Identity: 192/848 - (22%)
• Similarity: 324/848 - (38%)
• Gaps: 274/848 - (32%)

  Fly   118 KDDNKETALYLS----DDNFLILPGLESNSTHNITALAMHGDGSYSL-IAKDQTFATLIRGYQPS 177
            |.|.:|..|.||    |...|.:..::||.:..     .:|.....| |.....|  |..||
Zfish    87 KQDARELLLDLSFAQVDQQPLYIFVIKSNQSQK-----PYGPQKPVLAITVQHPF--LANGY--- 141

  Fly   178 KMGAVNLLRFVPQPDDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRH 242
                       |:.:||.| |..:.....:|::.|.:. |||.|.:.: ..::|.|   .|....
Zfish   142 -----------PRDEDLSH-AKALNLGNISENSFYLEF-SYSGNCMFI-ASVQVFF---LKCPAF 189

  Fly   243 TVDNLEFDKQYHVGVR-------TVNI---MNRLESDLQWLPIAVPS----CLDWYPYNYTLCPP 293
            |...::|::....|.|       .|.|   :...:|:..|   |.|.    |...|..:...|..
Zfish   190 TWKQMKFEETAARGSRRGVCVDGAVEISTPLTECQSNGTW---ASPQGSCVCSAEYQSSGDTCKA 251

  Fly   294 HKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTEL-----NYTLDQNRSHFY 353
            :.|.:|..|..         :|...||. ||..:|    .:..||..|     ...|...|.|
Zfish   252 NAPGSLLATPP---------SINDPRPA-LPPVHT----GVVVGGVLLLLIVTGVVLLFVRHH-- 300

  Fly   354 VPKITVLGSHFEVHLVAQSAGGKNVSGLTLDKVHRGVLLSEGNMVKLVLFIIVPICCILMLCSLT 418
                 .|..|.::.||::||       :|..:....:|.|:.:.|.      .|..|.::
Zfish   301 -----KLRGHQDMELVSESA-------VTQYRRQTELLDSKTSSVS------HPEVCRII----- 342

  Fly   419 FCRRNRS-EVQALQMDAKDAKASEFHLSL--MDSSGLLVTLSANESLEVMDELEVEPHSVLLQDV 480
              .:|:| |.:.....|:..:||::..:.  |....|.:..:.::|.:::|  .::.|.:.|:||
Zfish   343 --GQNQSAECKPCFPTAQIEEASQYDCAYEPMRPHTLQLKSTMSDSDQMLD--GIKDHLLCLRDV 403

  Fly   481 ------------LGEGAFGLVRRGVYKKR-----QVAVKLLKDE-PNDEDVYAFKCEIQMLKAVG 527
                        ||:|.||.|..|::..:     :||||..||. .::||:.:|..|.:|:|..
Zfish   404 LVERTKLQLSQKLGKGEFGAVYEGIFSPKIGQDIRVAVKTSKDVIHSEEDLESFLKEAEMMKHF- 467

  Fly   528 KHPNIVGIVGYSTRFSNQM-----MLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDN 587
            .|.|:|.::|.:..:..:.     ::::.|.....|.:|||.
Zfish   468 DHVNVVKLLGVALEWDPESSMVVPLVILPYMKHRDLHSFLRA----------------------- 509

  Fly   588 RRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENI 652
            .|::.:|
Zfish   510 TRYDDVP---------------------------------------------------------- 516

  Fly   653 GGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYAD 717
              .::|                                                        :..
Zfish   517 --MFVP--------------------------------------------------------HQS 523

  Fly   718 LLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLP 782
            ||.....:|.|||:|:....:||||||||.::..|..:.:||||||:.:|..|.||......|||
Zfish   524 LLRFMMDIAAGMEYLSLQGFLHRDLAARNCMLGDDLRVCVADFGLSKMMYSSNYYRHKSQDVKLP 588

  Fly   783 IKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQE 847
            ::|:|:||::..::|::||||||||.::|||:.|.:|||.||..:||..|.:|||:.:.:. ..:
Zfish   589 VRWMAIESVSDFIFTTKSDVWSFGVTMWEITSRGKVPYPGVSNYELLDYLEKGHRLSQGDN-DSK 652

  Fly   848 MFSLMESCWSSVPSHRPTFSALKHRLGGMILATNDVPERLKQ------LQAATESKLKSCDGLNS 906
            ::.||.|||...||.||:|..|...|..::.....:.:|::.      |:||.:.:    |...:
Zfish   653 LYELMLSCWHRDPSQRPSFGELHQSLSALLSELPPLEDRMESHYINLGLEAANDRQ----DSAQN 713

  Fly   907 KVE 909
            :||
Zfish   714 QVE 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	101/416 (24%)
si:ch73-40a2.1	XP_009301289.1	EphR_LBD	42..185	CDD:470656	30/124 (24%)
		PTKc	415..678	CDD:270623	99/403 (25%)