Protein Alignment tor and si:ch73-340m8.2

DIOPT Version :10

• Sequence 1: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_002665190.3
• Gene: si:ch73-340m8.2 / 100332982
• ZFINID: ZDB-GENE-110411-209
• Length: 480
• Species: Danio rerio
• Alignment Length: 524
• Identity: 132/524 - (25%)
• Similarity: 220/524 - (41%)
• Gaps: 117/524 - (22%)

  Fly   409 CCILMLCSLTFCRRNRSEVQALQMDAKDAKASEFHLSLMDSSGLLVTLSANESLEVMDELEVEPH 473
            ||....|.||                ||.:||      ::...:..::.:..|..:.| |.:...
Zfish    11 CCPCCPCCLT----------------KDQQAS------VNRDRVYTSIYSYPSRTIWD-LNLRKG 52

  Fly   474 SVLLQDVLGEGAFGLVRRGVYKKRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHP----NIVG 534
            .:|  :|.||..:.|     |.:|:.|.........:|..|..|..::.|.:|...|    |:
Zfish    53 DIL--EVTGETEYWL-----YVRRRTAKTDKSKSFIEEHGYVPKDFVKPLDSVEAEPWYFENV-- 108

  Fly   535 IVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKN--------LEQNVDNRRFN 591
                .||...:..||......|:   ||  .||..:..:.....||        ::|..::::|.
Zfish   109 ----KTRVEAKRCLLRPENKEGA---FL--VWKCDENNHYYLSVKNGPHARHYRIKQGENDQQFF 164

  Fly   592 RLPRNS---------------------IHDRIEDINNSMLSTVEEESESDQTHSSRCETYTL--- 632
            .:...:                     :|:....::..:..|:..:|:.:...||..:...|
Zfish   165 LVHHTTFQSLRKLIEFYSKHEGGLCAKLHEACVKLDQPVPQTLSFDSKCEIDRSSLTKQQKLGSG 229

  Fly   633 ----------TRITNAADNKGYGLEDIENIGGSYIPKTAEAPKD-RPKRKLK-------PQPKKD 679
                      ...|..|      :::.:.:..|.|....|..|| ..:|.||       .||...
Zfish   230 EFADVWQGLWNNTTEVA------IKEFKGVNYSDIQTEIEIMKDLHHERLLKLYAVCTTSQPMCI 288

  Fly   680 SKQDFKSDNKKR-IFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLA 743
            ..:..|:.:.|. :..:||..|            |:::.:||.|.|:..||.:: :||:|||||.
Zfish   289 VTELMKNGSLKTFLLRHKEKQD------------LEFSLMLDFAIQITEGMIYI-ENKIVHRDLR 340

  Fly   744 ARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVL 808
            |.|:|::..:|.|||||||::.....|  ::.....:||:||:|.|...:..|||:|||||||:|
Zfish   341 AENILLTEMQSCKIADFGLAQVNRPGN--QRISSDVRLPVKWMAPEIFDNGEYTSKSDVWSFGIL 403

  Fly   809 LYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSALKHRL 873
            |.||.|.|..|||.......::.:::|.||.||.||.:.::.:|..||.:.|..||||:.|:..|
Zfish   404 LTEIVTYGDDPYPGQDKMSCVRGIQRGERMPRPAGCPESLYGIMLLCWKANPKERPTFTELREML 468

  Fly   874 GGMI 877
            ..:|
Zfish   469 MALI 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tor	NP_476762.1	PTKc	479..873	CDD:270623	117/448 (26%)
si:ch73-340m8.2	XP_002665190.3	SH2	99..192	CDD:472789	15/103 (15%)
		Protein Kinases, catalytic domain	225..468	CDD:473864	85/263 (32%)