| Sequence 1: | NP_610315.1 | Gene: | U2A / 35713 | FlyBaseID: | FBgn0033210 | Length: | 265 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006296.1 | Gene: | ANP32A / 8125 | HGNCID: | 13233 | Length: | 249 | Species: | Homo sapiens |
| Alignment Length: | 140 | Identity: | 44/140 - (31%) |
|---|---|---|---|
| Similarity: | 72/140 - (51%) | Gaps: | 3/140 - (2%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 ELINQSMQYINPCRERELDLRGYKIPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLL 71
Fly 72 NNNRILRISEGLEEAVPNLGSIILTGNNLQELSDLEPLVGFTKLETICLLINPVSTKPNYREYMA 136
Fly 137 YKFPQLRLLD 146 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| U2A | NP_610315.1 | LRR_9 | 1..175 | CDD:405295 | 44/140 (31%) |
| leucine-rich repeat | 22..43 | CDD:275380 | 4/20 (20%) | ||
| leucine-rich repeat | 46..65 | CDD:275378 | 5/18 (28%) | ||
| leucine-rich repeat | 66..89 | CDD:275378 | 9/22 (41%) | ||
| leucine-rich repeat | 90..114 | CDD:275378 | 9/23 (39%) | ||
| ANP32A | NP_006296.1 | LRR 1. /evidence=ECO:0000269|PubMed:17567741 | 18..38 | 4/22 (18%) | |
| LRR 2. /evidence=ECO:0000269|PubMed:17567741 | 43..64 | 4/20 (20%) | |||
| LRR 3. /evidence=ECO:0000269|PubMed:17567741 | 65..87 | 9/21 (43%) | |||
| LRR_9 | <71..146 | CDD:405295 | 26/74 (35%) | ||
| LRR 4. /evidence=ECO:0000269|PubMed:17567741 | 89..110 | 9/20 (45%) | |||
| leucine-rich repeat | 90..114 | CDD:275380 | 9/23 (39%) | ||
| leucine-rich repeat | 115..141 | CDD:275380 | 6/25 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 147..249 | 44/140 (31%) | |||
| Necessary for tumor-suppressive function | 150..174 | ||||
| Interaction with E4F1. /evidence=ECO:0000250 | 165..249 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||