Protein Alignment U2A and CFAP410

DIOPT Version :10

• Sequence 1: NP_610315.1
• Gene: U2A / 35713
• FlyBaseID: FBgn0033210
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_047296936.1
• Gene: CFAP410 / 755
• HGNCID: 1260
• Length: 401
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 53/245 - (21%)
• Similarity: 81/245 - (33%)
• Gaps: 79/245 - (32%)

  Fly    14 QYINPCR----ERELDLRGYKIPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNN 74
            |..:|||    ....|......||.....|.....       |.:..|:.:....||..|.|..|
Human    40 QLASPCRRVWGSARADASSQGCPQTAQRAAASQIV-------NSISTLEPVSRCQRLSELYLRRN 97

  Fly    75 RILRISEGLEEAVPNLGSIILTGNNLQELSDLEPLVGFTKLETICLLINP-VSTKPN-YREYMAY 137
            ||                        ..|::|..|.|..:|..:.|..|| ..|.|: ||..:..
Human    98 RI------------------------PSLAELFYLKGLPRLRVLWLAENPCCGTSPHRYRMTVLR 138

  Fly   138 KFPQLRLLDFRKIKQKDRQAAQEFFRTKQGKDVLKEISRKSKMSAAAAIAAEAGNGKGRG----- 197
            ..|:|:.||.:.:.:::...|     ..:|:::               .||....|.|.|
Human   139 TLPRLQKLDNQAVTEEELSRA-----LSEGEEI---------------TAAPEREGTGHGGPKLC 183

  Fly   198 ---------SEGGRLANPQDMQRIREAIKRASSLAEVERLSQILQSGQLP 238
                     :|.||  :|.|.:      :.|:|.|:.||..:....||.|
Human   184 CTLSSLSSAAETGR--DPLDSE------EEATSGAQDERGLKPPSRGQFP 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:405295	35/166 (21%)
		leucine-rich repeat	22..43	CDD:275380	4/20 (20%)
		leucine-rich repeat	46..65	CDD:275378	2/18 (11%)
		leucine-rich repeat	66..89	CDD:275378	6/22 (27%)
		leucine-rich repeat	90..114	CDD:275378	4/23 (17%)
CFAP410	XP_047296936.1	PPP1R42	<75..155	CDD:455733	25/103 (24%)
		leucine-rich repeat	89..112	CDD:275382	10/46 (22%)
		leucine-rich repeat	114..142	CDD:275382	8/27 (30%)