DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2A and lrmda

DIOPT Version :9

Sequence 1:	NP_610315.1	Gene:	U2A / 35713	FlyBaseID:	FBgn0033210	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001018537.1	Gene:	lrmda / 553730	ZFINID:	ZDB-GENE-050522-285	Length:	234	Species:	Danio rerio

Alignment Length:	214	Identity:	59/214 - (27%)
Similarity:	87/214 - (40%)	Gaps:	46/214 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RELDLRGYKIPQIENLGATLDQFDTI----DLSDNDLRKLDNLPHLPRLKCLLLNNNRILRIS-- 80
            |.|||...::..:..|.| ..|.:.:    :|..||||    ||.||||..|.||.|::..|.
Zfish    38 RRLDLSFNQLRSLTGLKA-FSQLEELIVDNNLLGNDLR----LPRLPRLHTLTLNKNQLTDIEAL 97

  Fly    81 -EGLEEAVPNLGSIILTGNNLQELSDLEPLVGFTKLETICLLINPVSTKPNYREYMAYKFPQLRL 144
             |.|.|..|.|..:.|.||.    :....||...|.|         .....||.::.:|...|:.
Zfish    98 LEHLVEVTPALEYLSLLGNE----ACPNQLVSMDKDE---------DDYQRYRYFVLHKLTNLKF 149

  Fly   145 LDFRKIKQKDRQAAQ------EFFRTKQGKDVLKEISRKSKMSAAAAI---AAEAGNGK------ 194
            ||.|::.|.:|..||      :..:.|..:|...:...:|..:....:   :.:|.|.|
Zfish   150 LDTRRVTQWERSEAQARGAFMKVVKPKNDQDTASDTRSESIATPYTPLPRGSRDARNHKGVFTKC 214

  Fly   195 -----GRGSEGGR-LANPQ 207
                 |:.|||.| :.|.|
Zfish   215 RYVYYGKHSEGNRFIRNDQ 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:258718	48/165 (29%)
		leucine-rich repeat	22..43	CDD:275380	6/20 (30%)
		LRR_4	46..81	CDD:289563	16/41 (39%)
		leucine-rich repeat	46..65	CDD:275378	8/22 (36%)
		leucine-rich repeat	66..89	CDD:275378	9/25 (36%)
		leucine-rich repeat	90..114	CDD:275378	6/23 (26%)
lrmda	NP_001018537.1	leucine-rich repeat	38..58	CDD:275378	6/20 (30%)
		LRR_9	<40..164	CDD:317038	43/141 (30%)
		leucine-rich repeat	59..80	CDD:275378	8/24 (33%)
		leucine-rich repeat	81..107	CDD:275378	9/25 (36%)
		leucine-rich repeat	108..146	CDD:275378	11/50 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810