Protein Alignment U2A and f-cup

DIOPT Version :10

• Sequence 1: NP_610315.1
• Gene: U2A / 35713
• FlyBaseID: FBgn0033210
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001262544.1
• Gene: f-cup / 41677
• FlyBaseID: FBgn0028487
• Length: 802
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 68/331 - (20%)
• Similarity: 109/331 - (32%)
• Gaps: 105/331 - (31%)

  Fly     1 MVKLTPEL--------INQSMQYINPCRERELDLRGYKIPQIENLGATLDQFDTIDLSDNDLRKL 57
            :|:|.||:        :|.|...::     :|....|.:|::.:|..:.::|..::...:||..|
  Fly   191 LVELPPEIGKLEKLVRLNVSHNKLS-----QLPRAMYSLPELRHLNISYNEFVELNPDISDLHML 250

  Fly    58 D-------NLPHLP-------RLKCLLLNNNRILRISEGLEEAVPNLGSIILTGNNLQELSDLEP 108
            :       |:..||       ||..|||..|.|..:...|.. :.:|..|.|..|:|..|.  |.
  Fly   251 EFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVN-MRSLQKIDLMHNDLTSLP--ED 312

  Fly   109 LVGFTKLETICLLINPVSTKPNYR-------------------EYMAYKFPQLRLLDFRKIKQKD 154
            :....||:.:.|..|.:...|.:.                   :.|....|.|::||.|..|..:
  Fly   313 MGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITE 377

  Fly   155 RQAAQEFFRTKQGKDV---------------------------LKEISR-----------KSKMS 181
            ........|.....||                           :|.|.|           |:...
  Fly   378 LPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCGTTRILKTLHD 442

  Fly   182 AAAAIAAEAGNGKGRGSEGGRLANPQDMQRIREAIKRASSLAEVERLSQILQSGQLPDKFQHEME 246
            .|.|.|.|.|.|....|....::    :.|:|........:           .|..||.|.|:.:
  Fly   443 RAVAKAKEEGGGVDDASTSAGIS----VTRLRGGQMDDGDI-----------PGNFPDSFHHQQQ 492

  Fly   247 AVAQNG 252
               |||
  Fly   493 ---QNG 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:405295	48/241 (20%)
		leucine-rich repeat	22..43	CDD:275380	4/20 (20%)
		leucine-rich repeat	46..65	CDD:275378	6/32 (19%)
		leucine-rich repeat	66..89	CDD:275378	7/22 (32%)
		leucine-rich repeat	90..114	CDD:275378	7/23 (30%)
f-cup	NP_001262544.1	LRR	98..428	CDD:443914	50/244 (20%)
		leucine-rich repeat	111..140	CDD:275380
		leucine-rich repeat	158..180	CDD:275380
		leucine-rich repeat	181..203	CDD:275380	4/11 (36%)
		leucine-rich repeat	204..226	CDD:275380	4/26 (15%)
		leucine-rich repeat	227..249	CDD:275380	4/21 (19%)
		leucine-rich repeat	250..272	CDD:275380	4/21 (19%)
		leucine-rich repeat	273..295	CDD:275380	7/22 (32%)
		leucine-rich repeat	296..318	CDD:275380	7/23 (30%)
		leucine-rich repeat	319..340	CDD:275380	4/20 (20%)
		leucine-rich repeat	341..364	CDD:275380	1/22 (5%)
		leucine-rich repeat	389..410	CDD:275380	2/20 (10%)
		leucine-rich repeat	411..430	CDD:275380	3/18 (17%)
		leucine-rich repeat	627..650	CDD:275380
		LRR	<629..>778	CDD:443914
		leucine-rich repeat	651..669	CDD:275380
		leucine-rich repeat	697..719	CDD:275380
		leucine-rich repeat	720..743	CDD:275380
		leucine-rich repeat	744..766	CDD:275380