Protein Alignment U2A and Lrrc72

DIOPT Version :10

• Sequence 1: NP_610315.1
• Gene: U2A / 35713
• FlyBaseID: FBgn0033210
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001418815.1
• Gene: Lrrc72 / 298963
• RGDID: 1560395
• Length: 286
• Species: Rattus norvegicus
• Alignment Length: 195
• Identity: 58/195 - (29%)
• Similarity: 96/195 - (49%)
• Gaps: 21/195 - (10%)

  Fly     3 KLTPELINQSMQYINPCRERELDLRGYK--IPQIENLGATLDQFDTIDLSD-NDLR-------KL 57
            |::...:..|::.:    |.:|.:.|:|  |..:|...:..|..:.:|||. ..||       ||
  Rat    19 KVSENALPSSLKAL----EDQLKICGHKKDIDVLELFLSKKDLTEVVDLSRFKKLRYLWLHHNKL 79

  Fly    58 DNLPHLPRLKC---LLLNNNRILRISEGLEEAVPNLGSIILTGNNLQEL-SDLEPLVGFTKLETI 118
            ..:..|.|..|   |.||:|.:.:| |||.. :|:|..::|..|.|..: :.::.|.|...|:|:
  Rat    80 QGISFLTRNYCLAELYLNHNALFQI-EGLHN-LPSLNILLLHHNELTNIDATVKELKGMQNLKTL 142

  Fly   119 CLLINPVSTKPNYREYMAYKFPQLRLLDFRKIKQKDRQAAQEFFRTKQGKDVLKEISRKSKMSAA 183
            .|..||:|....||.|:.|..|.|.|||.::|..|:|:.....|..|: ..||:.|:...:..|:
  Rat   143 SLYQNPLSQYNLYRLYIIYHLPGLELLDRKEITAKERRNMITIFNHKK-THVLQSIAFGKRADAS 206

  Fly   184  183
              Rat   207  206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:405295	56/185 (30%)
		leucine-rich repeat	22..43	CDD:275380	5/22 (23%)
		leucine-rich repeat	46..65	CDD:275378	8/26 (31%)
		leucine-rich repeat	66..89	CDD:275378	9/25 (36%)
		leucine-rich repeat	90..114	CDD:275378	6/24 (25%)
Lrrc72	NP_001418815.1	leucine-rich repeat	49..68	CDD:275378	5/18 (28%)
		PPP1R42	50..190	CDD:455733	45/141 (32%)
		leucine-rich repeat	69..90	CDD:275378	6/20 (30%)
		leucine-rich repeat	91..112	CDD:275378	8/22 (36%)
		leucine-rich repeat	113..138	CDD:275378	6/24 (25%)
		leucine-rich repeat	139..150	CDD:275378	5/10 (50%)