Protein Alignment DCTN4-p62 and dctn4

DIOPT Version :9

• Sequence 1: NP_610311.1
• Gene: DCTN4-p62 / 35709
• FlyBaseID: FBgn0033206
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001025673.1
• Gene: dctn4 / 595065
• XenbaseID: XB-GENE-491837
• Length: 470
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 179/491 - (36%)
• Similarity: 262/491 - (53%)
• Gaps: 107/491 - (21%)

  Fly    20 PINTLFFCRHCPKLRCGFCVTHEIESHFCSNCLENIPSTEARHKKNCCANCFDCPCCQHTLSARA 84
            |::.|:|||:|.:||...||:||::||:|.:||||:||.||:.|||.||||||||||.||||.||
 Frog    23 PLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPCCMHTLSTRA 87

  Fly    85 STVPVVRKSEEAKEPKDGDSKGEATPPVPASSKPSAVPTTKKMYYLSCLSCRWTTRDVGIPDQGV 149
            :.:|       |..|.|           ||.:      |.||.|||:|..||||:||||:.|:.|
 Frog    88 TNIP-------APLPDD-----------PAKT------TMKKAYYLACGFCRWTSRDVGMADKSV 128

  Fly   150 ATGTWPDNECLYQARFNALVEYFQAVVLQEK--QEKLEFMRRK-----APKQHKF---------- 197
            |:|.|.:.|..:..|.|.|:||:|.:..:||  :::.:.:||:     |..||..
 Frog   129 ASGGWQEPENPHTQRINKLLEYYQQLAQKEKIERDRKKLVRRRNYMPLAFSQHTIHVADKYGRGT 193

  Fly   198 --------PSLTDRTGLTVSLIRRQIGWNDKAPKAKAVITPAEATAEVEGLPENIFTEPLNLRNV 254
                    ..:|..||||:     :.|.:.|..|.:|    |:|..|||.|||:.:|.|:||..|
 Frog   194 RLQRQRPGAPITALTGLTL-----KEGEDQKEIKIEA----AQAIEEVEPLPEDYYTRPINLTEV 249

  Fly   255 TTITQRHSQPADQPTAVGSLYPQRRSLWIKRSLRCRQCEHNLIKPEYHPTSIKYRIQHFASYHVP 319
            ||:.||..||..||.....|:|:.:.|.||||||||:|||||.|||::|||||::||..|..:||
 Frog   250 TTLDQRLLQPDFQPICASQLHPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVALSYVP 314

  Fly   320 EVVMVRCEQPLVAGKSNAILLKLTNPTIYDMT-IRLLTASPPEDPQLSTEATRVAKEEPISSSPL 383
            ||.::.... |...|.:.:||.|||| :.::| :.||.....:..::
 Frog   315 EVRIMSIPN-LRYMKESQVLLTLTNP-VENLTHVNLLPCEEGDQDEI------------------ 359

  Fly   384 LKAVGITLSRQNSTREVKRDVIDISNAEIVPLESEFVLNQRDDSKEFDE--DVQLSTEEPKFIVW 446
                       |||.:|           ||| ..|.:|..:|.:.|:||  :.|...::|..:.:
 Frog   360 -----------NSTAKV-----------IVP-NKELILAGKDAAAEYDELAEPQDFQDDPDVVAF 401

  Fly   447 RKGNKVLLRLQFTPAEELSGLADVVLGFYMQYTYVN 482
            ||.|||.:.::.:|.:|   ...|::.|.:::.:.|
 Frog   402 RKANKVGVFIKVSPLQE---KGKVIVSFKLKHDFRN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCTN4-p62	NP_610311.1	Dynactin_p62	20..363	CDD:283218	154/368 (42%)
dctn4	NP_001025673.1	Dynactin_p62	23..>339	CDD:368474	149/349 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5046
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9430
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2922
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D353286at33208
OrthoFinder	1	1.000	-	-		FOG0007521
OrthoInspector	1	1.000	-	-		oto104045
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060