Protein Alignment DCTN4-p62 and dctn4

DIOPT Version :9

• Sequence 1: NP_610311.1
• Gene: DCTN4-p62 / 35709
• FlyBaseID: FBgn0033206
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001017782.2
• Gene: dctn4 / 550479
• ZFINID: ZDB-GENE-050417-306
• Length: 467
• Species: Danio rerio
• Alignment Length: 506
• Identity: 181/506 - (35%)
• Similarity: 261/506 - (51%)
• Gaps: 99/506 - (19%)

  Fly     2 SFMQPSPVKYAC--SCGILNPINTLFFCRHCPKLRCGFCVTHEIESHFCSNCLENIPSTEARHKK 64
            :.:||..|.|..  ...|..|::.|:|||:|.:||...||:||::||||.:||||:||.||:.||
Zfish     3 TLLQPEKVLYLVRGEKKIRVPLSQLYFCRYCSELRSLECVSHEVDSHFCPSCLENMPSAEAKLKK 67

  Fly    65 NCCANCFDCPCCQHTLSARASTVPVVRKSEEAKEPKDGDSKGEATPPVPASSKPSAVPTTKKMYY 129
            |.||||||||||.||||.||:.:|.                     |:|  ..|:.. |.||.||
Zfish    68 NRCANCFDCPCCMHTLSTRATNIPA---------------------PLP--DDPTKT-TMKKAYY 108

  Fly   130 LSCLSCRWTTRDVGIPDQGVATGTWPDNECLYQARFNALVEYFQAVVLQEKQEK-LEFMRRKAP- 192
            |:|..||||:||||:.|:.||:|.|.:.|..:..|.|.|:||:|.:..:||.|: .:.|.|:.|
Zfish   109 LACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRINKLIEYYQQLAQREKLERDRKKMARRRPF 173

  Fly   193 -----KQHKFPSLTDRTGLTVSLIRRQIGWNDKAP--------------KAKAVITPAEATAEVE 238
                 .||.. .:.::.||...|.|::.|    ||              :.:..|.||:|..|||
Zfish   174 MPQAFSQHTI-HVVEKYGLGTRLQRQRSG----APISALYGLSLKEGEDQKEITIEPAQALDEVE 233

  Fly   239 GLPENIFTEPLNLRNVTTITQRHSQPADQPTAVGSLYPQRRSLWIKRSLRCRQCEHNLIKPEYHP 303
            .|||:.:|.|:||..|||:.||..||..||.....|:|:.:.|.:|||||||:|||||.|||::|
Zfish   234 PLPEDYYTRPVNLPEVTTLRQRLLQPDFQPAGASQLHPRHKHLLMKRSLRCRKCEHNLSKPEFNP 298

  Fly   304 TSIKYRIQHFASYHVPEVVMVRCEQPLVAGKSNAILLKLTNPTIYDMTIRLLTASPPEDPQLSTE 368
            ||||::||..|..::|||.::.... |...|.:.:||.||||......:.|.|....:...:
Zfish   299 TSIKFKIQLVAVSYIPEVRIMSIPN-LRHMKESQVLLTLTNPVENITHVSLYTCEEEDQDDI--- 359

  Fly   369 ATRVAKEEPISSSPLLKAVGITLSRQNSTREVKRDVIDISNAEIVPLESEFVLNQRDDSKEFDE- 432
                                      |||.:|           :|| ..|.||..:|.:.|:||
Zfish   360 --------------------------NSTAKV-----------LVP-SKELVLAGKDAAAEYDEL 386

  Fly   433 -DVQLSTEEPKFIVWRKGNKVLLRLQFTPAEELSGLADVVLGFYMQYTYVN 482
             :.|...::|..:.:||.||:...::..|.:|   ..||.:.|.:::.:.|
Zfish   387 AEPQGFQDDPDVVAFRKSNKIGFFIKVIPQQE---EGDVTVAFKLRHDFRN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCTN4-p62	NP_610311.1	Dynactin_p62	20..363	CDD:283218	151/363 (42%)
dctn4	NP_001017782.2	Dynactin_p62	23..350	CDD:310244	150/356 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573858
Domainoid	1	1.000	133	1.000	Domainoid score	I5056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9430
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2899
OMA	1	1.010	-	-		QHG58753
OrthoDB	1	1.010	-	-		D353286at33208
OrthoFinder	1	1.000	-	-		FOG0007521
OrthoInspector	1	1.000	-	-		oto40598
orthoMCL	1	0.900	-	-		OOG6_104002
Panther	1	1.100	-	-	LDO	PTHR13034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910