Protein Alignment DCTN4-p62 and dnc-4

DIOPT Version :9

• Sequence 1: NP_610311.1
• Gene: DCTN4-p62 / 35709
• FlyBaseID: FBgn0033206
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_501344.1
• Gene: dnc-4 / 177600
• WormBaseID: WBGene00016124
• Length: 413
• Species: Caenorhabditis elegans
• Alignment Length: 470
• Identity: 123/470 - (26%)
• Similarity: 186/470 - (39%)
• Gaps: 122/470 - (25%)

  Fly     4 MQPSPVKYACSCGILNPINTLFFCRHCPKLRCGFCVTHEIESHFCSNCLENIPSTEARHKKNCCA 68
            :|.|.:||.|:||....:..|.|||:|.|::|..|...|:::.||..|||.....|||.||:.||
 Worm     5 LQYSRIKYECTCGKFRTLPDLVFCRYCFKIKCDDCSLGEVDNIFCPRCLEPSSVPEARLKKHKCA 69

  Fly    69 NCFDCPCCQHTLSARASTVPVVRKSEEAKEPKDGDSKGEATPPVPASSKPSAVPTTKKMYYLSCL 133
            :|.|||.|.:.||||                                       |.....||.|.
 Worm    70 SCNDCPKCANVLSAR---------------------------------------TENDNVYLVCQ 95

  Fly   134 SCRWTTRDVGIPDQGVATGTWPDNECLYQARFNALVEYFQAVVLQEKQEKLEFMRRKAPKQHKFP 198
            .|||::|:....|| ..|.:||..|       |.||.....|....|  :||.: ..|||..|
 Worm    96 YCRWSSREANQEDQ-ENTKSWPTKE-------NPLVNQLGEVTAYMK--RLELI-ENAPKDLK-- 147

  Fly   199 SLTDRTG--LTVSLIRRQIGWNDKAPKAKAVITP------AEATAEVEGLPENIFTEPLNLRNVT 255
              ..::|  .|...::.:.|:.....|.|..:.|      |.|..|...|.:.|.....:||.:.
 Worm   148 --KGKSGKAWTAFHLKDKFGFQQMVDKRKKALAPEMNPVDAHAPTEAPTLEDEIKERTDDLRTLD 210

  Fly   256 TITQRHSQPADQPTAVGSLYPQRRSLWIKRSLRCRQCEHNLIKPEYHPTSIKYRIQHFASYHVPE 320
            .|..:......:|     |.|.:..|..:..:||.:||..|||.::..|:.|::|..||...||:
 Worm   211 QIIMQPLINISEP-----LLPVQVPLAGRVQVRCDECERTLIKRDFGVTTFKFKISSFARQFVPD 270

  Fly   321 VVMVRCEQPLVAGKSNAILLKLTNPTIYDMTIRLLTASPPEDPQLSTEATRVAKEEPISSSPLLK 385
            :.|.|....|..|:::.:.|.:||                                 :|||
 Worm   271 IRMSRPVDDLKVGETSHVFLSITN---------------------------------LSSS---- 298

  Fly   386 AVGITLSRQ--NSTREVKRDVIDISNAEIVPLESEFVLNQRDDSKEFDEDVQ-LSTEEPKFIVWR 447
            |:.:|::.|  |...:...|.|.:    ::|           .|:..|.... :..::...||:|
 Worm   299 AMDLTIAPQSGNGFIQCSSDPIQL----LLP-----------SSRASDTAAPGVHADQSDVIVFR 348

  Fly   448 KGNKVLLRLQFTPAE 462
            :.|:|.|||...|.|
 Worm   349 QHNRVGLRLDVIPTE 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCTN4-p62	NP_610311.1	Dynactin_p62	20..363	CDD:283218	94/350 (27%)
dnc-4	NP_501344.1	Dynactin_p62	25..>103	CDD:283218	37/116 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156175
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3896
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9430
Inparanoid	1	1.050	131	1.000	Inparanoid score	I3195
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58753
OrthoDB	1	1.010	-	-		D353286at33208
OrthoFinder	1	1.000	-	-		FOG0007521
OrthoInspector	1	1.000	-	-		oto20110
orthoMCL	1	0.900	-	-		OOG6_104002
Panther	1	1.100	-	-	LDO	PTHR13034
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3688
SonicParanoid	1	1.000	-	-		X5650
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840