Protein Alignment Rdh1 and CBR3

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001227.1
• Gene: CBR3 / 874
• HGNCID: 1549
• Length: 277
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 78/277 - (28%)
• Similarity: 118/277 - (42%)
• Gaps: 62/277 - (22%)

  Fly    44 KVFIVTGANTGIGKETALEIARR-GGTVYLACRDMNRCEKARKDIIKETNNQNIFSR--ELDLSS 105
            :|.:|||||.|||...|.|:.|: .|.|.|..||:.|.:.|    :::...:.:..|  :||:..
Human     6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAA----VQQLQAEGLSPRFHQLDIDD 66

  Fly   106 LDSIRKFVDGFKKEQPKLHVLINNAGV-MRCPKTLTKD-GYELQLGVNHIGHFLLTNLLLDVLKN 168
            |.|||...|..:||...|:||:|||.| .:....:..| ..|:.|..|......:.|.||.::|
Human    67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMK- 130

  Fly   169 SAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLA-----------------------------Y 204
             ...|:|.:|||...|...|.::...|:.:.|.|.                             |
Human   131 -PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPY 194

  Fly   205 SQSKLANVLFTRELAKRLE----GSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIWPLL 265
            ..|||...:.:|.||:||:    ...:.|||..||.|.|::...                  ..:
Human   195 GVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGK------------------DSI 241

  Fly   266 KTPKSGAQTSIYAALDP 282
            :|.:.||:|.:|.||.|
Human   242 RTVEEGAETPVYLALLP 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	78/277 (28%)
CBR3	NP_001227.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	78/277 (28%)