Protein Alignment Rdh1 and PBR1

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_014218.2
• Gene: PBR1 / 855540
• SGDID: S000005125
• Length: 407
• Species: Saccharomyces cerevisiae
• Alignment Length: 351
• Identity: 99/351 - (28%)
• Similarity: 155/351 - (44%)
• Gaps: 53/351 - (15%)

  Fly    16 PATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANT-GIGKETALEIARRGGTVYLACRDMNR 79
            |..:..|.  :|.:.:|...|.:....|||::||||.: |:|...|.::|..|..:.:..|:::.
Yeast    28 PYVLATGA--IKYWSRGPSNTWERKLHGKVYLVTGATSQGMGTSVAYKMAELGAQLIILTREVDE 90

  Fly    80 -----CEKARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQP--KLHVLINNAGVMR--- 134
                 ||:.|    ::|.|:.||..:.|||:|..||||...:....|  :|..:|..:|.|.
Yeast    91 WVTEWCEELR----EKTKNELIFVEKCDLSNLWEIRKFATSWLDNSPPRRLDGVIVMSGDMEPWG 151

  Fly   135 CPK------TLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPS---RIVVVSSLAHARGSINVA 190
            .||      ..:|||.|||:..|::..|.|.|||....|...|.   ||::.:......|.||:.
Yeast   152 IPKISLPQRRSSKDGLELQIATNYVAIFHLLNLLQPSFKAQPPDRDVRIILATCWLQVVGDINIE 216

  Fly   191 D-LNSEKSYDEGLA-YSQSKLANVLFTRELAKRL--------------EGSGVTVNALHPGVVDT 239
            | |.....|...|. ::.|||...|...||.:||              .|..||:..:.||.:.:
Yeast   217 DPLWQNAKYKSALKFFASSKLQLGLSMMELQRRLTEDIKNQKTNGAERTGKNVTITMVQPGTMRS 281

  Fly   240 E-----LARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPE-----LKNISGLYFSD 294
            .     ::.........|....|.|::|...|:.:.|.|:.:||.:.||     ||:....|.||
Yeast   282 NSLRRVISNGSVVLLIILYCILLYPILWLFTKSGRRGDQSFLYALMTPELEEVNLKDTKVKYISD 346

  Fly   295 CKPKPVASGALDD-KVAKFLWAESEK 319
            |.....|....|| ::.|.|:..:|:
Yeast   347 CSIVKFARKEFDDEELQKKLFDNTER 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	93/320 (29%)
PBR1	NP_014218.2	retinol-DH_like_SDR_c_like	53..367	CDD:212492	92/317 (29%)