DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and Tic32-IVa

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_849428.1	Gene:	Tic32-IVa / 828442	AraportID:	AT4G23430	Length:	322	Species:	Arabidopsis thaliana

Alignment Length:	315	Identity:	125/315 - (39%)
Similarity:	174/315 - (55%)	Gaps:	34/315 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 TKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRE 100
            |...|.||...|||||::|||.|||..::.||..|.:|.|:.:...|.::||:|:.....:...|
plant    22 THGVDGTGLTAIVTGASSGIGVETARVLSLRGVHVVMAVRNTDSGAKVKEDIVKQVPGAKLDVME 86

  Fly   101 LDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDV 165
            |||||:.|:|||...:|.....|::||||||:|.||..|:||..|||...||:||||||.||||.
plant    87 LDLSSMQSVRKFASEYKSTGLPLNLLINNAGIMACPFMLSKDNIELQFATNHLGHFLLTKLLLDT 151

  Fly   166 LKNSA-----PSRIVVVSSLAHARG---SINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRL 222
            :|:::     ..|||.:||.||...   .:....:|.:.||....||.||||.|||...||.|:|
plant   152 MKSTSRESKREGRIVNLSSEAHRFSYPEGVRFDKINDKSSYSSMRAYGQSKLCNVLHANELTKQL 216

  Fly   223 --EGSGVTVNALHPGVVDTELARNWAFFQTNL-------VKFFLKPMIWPLLKTPKSGAQTSIYA 278
              :|..:|.|:||||.:.|.|.|   :|...|       .|:        :||:...||.|:.|.
plant   217 KEDGVNITANSLHPGAIMTNLGR---YFNPYLAVAVGAVAKY--------ILKSVPQGAATTCYV 270

  Fly   279 ALDPELKNISGLYFSD---CKPKPVASGALDDKVAKFLWAESEKWTGLDKLEANN 330
            ||:|::..:||.||.|   .||.|:..   |.::||.:|..|.|.|.....|:::
plant   271 ALNPQVAGVSGEYFQDSNIAKPLPLVK---DTELAKKVWDFSTKLTDSQSGESSS 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	122/301 (41%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	118/293 (40%)
Tic32-IVa	NP_849428.1	retinol-DH_like_SDR_c_like	29..306	CDD:212492	117/290 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I1212
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D921996at2759
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm1091
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780