DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2064 and DHRS12

DIOPT Version :9

Sequence 1:NP_610310.2 Gene:CG2064 / 35708 FlyBaseID:FBgn0033205 Length:330 Species:Drosophila melanogaster
Sequence 2:NP_001364858.1 Gene:DHRS12 / 79758 HGNCID:25832 Length:320 Species:Homo sapiens


Alignment Length:225 Identity:98/225 - (43%)
Similarity:133/225 - (59%) Gaps:15/225 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 LKEYMQGG--KFTKD-------TDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCE 81
            |:||.:.|  ...||       ....|:||:|||.|:||||.||||||:|||||:|.|||....|
Human    14 LREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAE 78

  Fly    82 KARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYEL 146
            .||.:||:|:.|||||...:|||....|.|||:.||:|. ||||||||||.|...:.||:||.|.
Human    79 DARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEK 142

  Fly   147 QLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKS-YDEGLAYSQSKLA 210
            ....|.:|.::||..|:.||:.....|::.|||.......:|..||.||:: :|..:.|:|:|..
Human   143 NFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQ 207

  Fly   211 NVLFTRELAKRLEG-SGVTVNALHPGVVDT 239
            .|:.|...|   :| ..:..:::|||..||
Human   208 QVVLTERWA---QGHPAIHFSSMHPGWADT 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2064NP_610310.2 PRK06197 40..322 CDD:235737 92/202 (46%)
NADB_Rossmann 43..317 CDD:304358 92/199 (46%)
DHRS12NP_001364858.1 NADB_Rossmann 40..>235 CDD:419666 92/199 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1208
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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