DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and si:dkey-174n20.1

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_005165244.1	Gene:	si:dkey-174n20.1 / 796174	ZFINID:	ZDB-GENE-030131-7890	Length:	308	Species:	Danio rerio

Alignment Length:	301	Identity:	117/301 - (38%)
Similarity:	184/301 - (61%)	Gaps:	16/301 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YFLKEYMQGGKFTKDTDE-TGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDI 87
            :.:.::|:..::..|... .||..::||.|:|||||||:.:|.||..|.:||||..:..||.::|
Zfish    14 FLVLKWMKRRRYCTDLKRLDGKTVLITGGNSGIGKETAVALAMRGARVIIACRDEEKARKAVREI 78

  Fly    88 IKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTL--TKDGYELQLGV 150
            ...::|.|:...|:||:::.|||:|...|.:::.:|.:||||||:   |..|  |.|.:.:..||
Zfish    79 KARSHNMNVLHMEVDLANMRSIREFSKTFLQKEKRLDILINNAGM---PGVLDWTDDNFSMCFGV 140

  Fly   151 NHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYD--EGLAYSQSKLANVL 213
            ||:||||||||||..||.|:|||::.::..::....:|..|||    |:  ....|.:|||||:.
Zfish   141 NHLGHFLLTNLLLPRLKESSPSRVINLTCSSYKYQKLNFQDLN----YNLFPFFTYCRSKLANIY 201

  Fly   214 FTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYA 278
            ||:|||:.:||.|||..|:|||.|.:    .|....:.|.:...:.:::....:.::||||.:|.
Zfish   202 FTQELARMMEGKGVTAYAVHPGYVRS----RWTCHFSVLYQILAQVVMFMFFVSCEAGAQTVVYC 262

  Fly   279 ALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEK 319
            |:..|:...:|.||:||:|.|:.:.|.|..|||.||..||:
Zfish   263 AVSDEVLPRNGGYFTDCRPAPLKAFARDSGVAKKLWEASER 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	115/285 (40%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	113/277 (41%)
si:dkey-174n20.1	XP_005165244.1	PRK06197	28..304	CDD:235737	116/287 (40%)
si:dkey-174n20.1	XP_005165244.1	NADB_Rossmann	34..301	CDD:304358	113/277 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830