Protein Alignment Rdh1 and hsd17b12

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001017234.1
• Gene: hsd17b12 / 549988
• XenbaseID: XB-GENE-945229
• Length: 320
• Species: Xenopus tropicalis
• Alignment Length: 291
• Identity: 75/291 - (25%)
• Similarity: 113/291 - (38%)
• Gaps: 73/291 - (25%)

  Fly     7 CLLSPLIMWPATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVY 71
            |||....:|  .:|.|       .|.|      ...||..:||||..||||..|.|:|:||..:.
 Frog    35 CLLDGARVW--VLGSG-------AQVG------PRIGKWAVVTGATDGIGKAYAEELAKRGMNIV 84

  Fly    72 LACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLDSIR------KFVDGFKKEQPKLHVLINNA 130
            |..|...:.|:..|. |||.     |..|..:.:.|..:      :...|.:  ..::.||:||.
 Frog    85 LISRSPEKLEEVAKQ-IKEK-----FKVETKIIAADFGKPTEIYGRIESGLR--DLEIGVLVNNV 141

  Fly   131 GVMRCPKTLTKDGYELQLGVNHIGHFL----LTNLL-----LDVLKNSAPSRIVVVSSLAHARGS 186
            ||          .||      |..:||    |.|.|     :::......:|:|:...|...||.
 Frog   142 GV----------SYE------HPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGV 190

  Fly   187 I-NVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQT 250
            | |::..:..........||.:|.....|:|.|.......||||.::.|..|.|:||:
 Frog   191 ILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKLAK------- 248

  Fly   251 NLVKFFLKPMIWPLLKTPKSGAQTSIYAALD 281
                  ::...|     .|...:|.:.:||:
 Frog   249 ------IRKPTW-----DKPSPETYVQSALN 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	67/255 (26%)
hsd17b12	NP_001017234.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	67/255 (26%)