DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and rdh14

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001017231.1	Gene:	rdh14 / 549985	XenbaseID:	XB-GENE-1018384	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	162/329 - (49%)
Similarity:	210/329 - (63%)	Gaps:	23/329 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SPLIMWPATIGVG---IYFLKEYMQ-----GGKFTKDTDETGKVFIVTGANTGIGKETALEIARR 66
            ||.:|..|.:.:|   |..::..:.     ||....    .||..|:||||.||||.||.|:.::
Frog     5 SPALMVAAAVALGGGLILVVRRLLSNSVRAGGSGLM----RGKTVIITGANCGIGKATAAELVKQ 65

  Fly    67 GGTVYLACRDMNRCEKARKDIIKETNNQ-NIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNA 130
            ...|.|||||..|.|:|..::.:|...: .|..::|||.||.|:|:|.....||:|:|.||||||
Frog    66 EARVILACRDQGRAEEAAAELRREAGERGEIVIKQLDLGSLQSVRRFCQEVLKEEPRLDVLINNA 130

  Fly   131 GVMRCPKTLTKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSE 195
            ||.:||.|.|:||:|:|.||||:||||||:.||.:||:|||||||||||..:..|.||..|||||
Frog   131 GVFQCPYTKTEDGFEMQFGVNHLGHFLLTHHLLGLLKSSAPSRIVVVSSKLYKYGEINFDDLNSE 195

  Fly   196 KSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPM 260
            |||.....||:|||||:|||||||.||||:||||||||||:|.|.|.|:     .| :...:||:
Frog   196 KSYSRSFGYSRSKLANILFTRELASRLEGTGVTVNALHPGIVRTNLGRH-----IN-IPILIKPL 254

  Fly   261 I----WPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEKWT 321
            .    |...|:|:.|||||||.|..||::.:||.||.:.|.:.:...|:||.||:.||..||...
Frog   255 FNVVSWAFFKSPEEGAQTSIYLASSPEVEGVSGSYFGNSKEEELLPKAMDDLVARKLWDISEVMV 319

  Fly   322 GLDK 325
            ||.|
Frog   320 GLIK 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	151/286 (53%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	149/278 (54%)
rdh14	NP_001017231.1	NADB_Rossmann	42..315	CDD:389744	149/278 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960