DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2064 and Rdh14

DIOPT Version :9

Sequence 1:	NP_610310.2	Gene:	CG2064 / 35708	FlyBaseID:	FBgn0033205	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001102746.1	Gene:	Rdh14 / 500629	RGDID:	1565196	Length:	334	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	149/298 - (50%)
Similarity:	196/298 - (65%)	Gaps:	22/298 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKE-----------TNNQNI 96
            ||..::||||:|:|:.||.|:.|.|..|.:.|||..|.|:|...:.:|           |:.| :
  Rat    44 GKTVLITGANSGLGRATAGELLRLGARVIMGCRDRARAEEAAGQLRQELGQAGGLGPDATDGQ-L 107

  Fly    97 FSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTNL 161
            ..:||||:||.|:|.|.....:|:|:|.||||||||.:||.|.|:||:|:|.||||:||||||||
  Rat   108 VVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFQCPYTKTEDGFEMQFGVNHLGHFLLTNL 172

  Fly   162 LLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSG 226
            ||.:||:|||||||||||..:..|.||..|||||:||::...||:|||||:|||||||.||||:.
  Rat   173 LLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELAHRLEGTN 237

  Fly   227 VTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMI----WPLLKTPKSGAQTSIYAALDPELKNI 287
            ||||.||||:|.|.|.|:..      :....:|:.    |...|||..|||||||.|..|:::.:
  Rat   238 VTVNVLHPGIVRTNLGRHIH------IPLLARPLFNLVSWAFFKTPLEGAQTSIYLASSPDVEGV 296

  Fly   288 SGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGLDK 325
            ||.||.|||.:.:...|:|:.||:.||..||...|:.|
  Rat   297 SGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2064	NP_610310.2	PRK06197	40..322	CDD:235737	147/293 (50%)
CG2064	NP_610310.2	NADB_Rossmann	43..317	CDD:304358	145/288 (50%)
Rdh14	NP_001102746.1	PRK06197	43..332	CDD:235737	147/294 (50%)
Rdh14	NP_001102746.1	NADB_Rossmann	44..326	CDD:304358	145/288 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730