Protein Alignment Rdh1 and hsd17b11

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001011304.1
• Gene: hsd17b11 / 496757
• XenbaseID: XB-GENE-1004190
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 280
• Identity: 75/280 - (26%)
• Similarity: 116/280 - (41%)
• Gaps: 55/280 - (19%)

  Fly    13 IMWPATIGVGIY---FLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETA-----LEIARRGGT 69
            |:|...:.|..|   |:|.::.    .|.....|:|.::|||..||||.||     ||..
 Frog     7 IVWLLLVIVYSYLESFVKLFIP----LKRKSVKGEVVLITGAGHGIGKITAQIFGELESV----- 62

  Fly    70 VYLACRDMNR------CEKARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLIN 128
              |...|:|:      .||.||      ....:::..:|.|..:.|....:..|:|...:.:|||
 Frog    63 --LVLWDINKQGVEETAEKCRK------GGAKVYTYVVDCSKREEINTAANKVKQEVGDVTILIN 119

  Fly   129 NAGVMRCPKTLTKDGYELQ--LGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVAD 191
            |||::.|...||....:::  ..||.:.||..|...|..:..:....||.|:|.|...|...:.|
 Frog   120 NAGIIFCADVLTLQDQQIEKIFEVNILAHFWTTRAFLPSMLRNNHGHIVTVASSAGFVGVQFMVD 184

  Fly   192 LNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFF 256
            ..|.|.  ..|.|.::..|.:|       .|..||:..:.|.|..|||...:|.:.
 Frog   185 YCSTKF--AALGYHKALTAELL-------ALGKSGIKTSCLCPVFVDTGFVKNPSL--------- 231

  Fly   257 LKPMIWPLLKTPKSGAQTSI 276
               .:.|:|: |:..|||.:
 Frog   232 ---RLAPVLQ-PEEVAQTLV 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	68/247 (28%)
hsd17b11	NP_001011304.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	67/245 (27%)