Protein Alignment Rdh1 and rdh13

DIOPT Version :10

• Sequence 1: NP_610310.2
• Gene: Rdh1 / 35708
• FlyBaseID: FBgn0033205
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001011000.1
• Gene: rdh13 / 496409
• XenbaseID: XB-GENE-965068
• Length: 329
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 160/305 - (52%)
• Similarity: 205/305 - (67%)
• Gaps: 1/305 - (0%)

  Fly    22 GIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKD 86
            |...||:|..||.........|:..||||||||||||||||:|:|||.:.:|||||.:||.|.:|
 Frog    17 GAILLKDYTGGGNCPSKASIIGQTVIVTGANTGIGKETALELAKRGGRIIMACRDMGKCENAARD 81

  Fly    87 IIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVN 151
            |..:|.|.|:|:|.|||:|..||::|......|:.::.||||||.|||||...|:|.:|:|.|||
 Frog    82 IRGKTLNHNVFARHLDLASSKSIKEFAKTIINEEERVDVLINNAAVMRCPHWKTEDNFEMQFGVN 146

  Fly   152 HIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSE-KSYDEGLAYSQSKLANVLFT 215
            |:||||||||||:.:|.|..|||:.||||||..|.|:..|||.| |.|:...||.||||||||||
 Frog   147 HLGHFLLTNLLLEKMKRSENSRIINVSSLAHIAGDIDFDDLNWEKKKYNTKAAYCQSKLANVLFT 211

  Fly   216 RELAKRLEGSGVTVNALHPGVVDTELARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAAL 280
            .||||||:|:.:|.|:|||||.||||.|:....|:......|.|:.|.|:|:||..||.|:|.|:
 Frog   212 NELAKRLQGTKLTANSLHPGVADTELGRHTGMHQSAFSSTILAPLFWFLVKSPKQAAQPSVYLAV 276

  Fly   281 DPELKNISGLYFSDCKPKPVASGALDDKVAKFLWAESEKWTGLDK 325
            ...|:.:||.||:..|.|..|..|||::.|:.||.||.|...|::
 Frog   277 AENLQGVSGKYFNALKEKEPAPQALDEESARKLWEESAKLVHLEE 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdh1	NP_610310.2	Rossmann-fold NAD(P)(+)-binding proteins	43..317	CDD:473865	150/274 (55%)
rdh13	NP_001011000.1	retinol-DH_like_SDR_c	38..313	CDD:212495	150/274 (55%)